EXOC3 and BUB3

Data Source:
BioGRID (two hybrid)

		EXOC3	BUB3
Description		exocyst complex component 3	BUB3 mitotic checkpoint protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Golgi Apparatus Cytosol Growth Cone Midbody Secretory Granule Membrane Presynaptic Membrane Perinuclear Region Of Cytoplasm	Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Cytosol Mitotic Checkpoint Complex Bub1-bub3 Complex
	Molecular Function	SNARE Binding Protein Binding Cadherin Binding	Protein Binding Ubiquitin Binding
	Biological Process	Exocytosis Protein Transport Exocyst Localization	Mitotic Sister Chromatid Segregation Ubiquitin-dependent Protein Catabolic Process Mitotic Spindle Assembly Checkpoint Attachment Of Spindle Microtubules To Kinetochore Anaphase-promoting Complex-dependent Catabolic Process Protein Localization To Kinetochore Cell Division Meiotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Inactivation of APC/C via direct inhibition of the APC/C complex Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Cdc20:Phospho-APC/C mediated degradation of Cyclin A APC/C:Cdc20 mediated degradation of mitotic proteins APC-Cdc20 mediated degradation of Nek2A Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Hypospadias ( 25108383) Red blood cell count ( 32888494) Ulcerative colitis ( 21297633)	Body mass index ( 28892062) Left-handedness ( 32989287) Menopause (age at onset) ( 24045676) Right lateral prefrontal cortical growth ( 29682794)
Interacting Genes		10 interacting genes: APP BIRC6 BUB3 EXOC2 FSD2 GMCL1 MLH1 PPP1R12C RALA VAMP2	17 interacting genes: BUB1 BUB1B CPNE1 EXOC3 HDAC1 HDAC2 PARP1 PARP2 PSTPIP1 PTEN RBBP7 RPL37A SUGT1 THRA TOP1 UBA1 WBP4
Entrez ID		11336	9184
HPRD ID		09738	04761
Ensembl ID		ENSG00000180104	ENSG00000154473
Uniprot IDs		A0A024QYZ6 O60645 Q69YP2	A0A140VJF3 O43684
PDB IDs
Enriched GO Terms of Interacting Partners?
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