LYST and PCBP4

Data Source:
BioGRID (two hybrid)

		LYST	PCBP4
Description		lysosomal trafficking regulator	poly(rC) binding protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Microtubule Cytoskeleton Membrane	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Protein Kinase Binding	DNA Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding
	Biological Process	Phagocytosis Lysosome Organization Protein Localization Protein Transport Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus	DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Regulation Of Gene Expression Regulation Of MRNA Stability Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process
Pathways			TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Transcriptional activation of cell cycle inhibitor p21 FOXO-mediated transcription of cell cycle genes
Drugs
Diseases		Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS		Basophil percentage of white cells ( 32888494) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Systemic lupus erythematosus ( 26502338 19838195)
Interacting Genes		24 interacting genes: ATN1 CALM1 CELF4 CENPJ CNTROB CSNK2B DNAJC14 EFS ESRRA ESS2 HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ YWHAZ ZNF521	5 interacting genes: LYST PCBP1 QKI RBFOX1 RNF138
Entrez ID		1130	57060
HPRD ID		06060	16343
Ensembl ID		ENSG00000143669	ENSG00000090097
Uniprot IDs		Q99698	A0A024R2Y0 C9J0A4 P57723
PDB IDs
Enriched GO Terms of Interacting Partners?
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