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LYST and NCDN
Data Source:
HPRD
(two hybrid, in vivo)
LYST
NCDN
Description
lysosomal trafficking regulator
neurochondrin
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytosol
Microtubule Cytoskeleton
Membrane
Nucleus
Cytosol
Endosome Membrane
Membrane
Axon
Dendrite
Neuronal Cell Body
Perikaryon
Postsynapse
Molecular Function
Protein Binding
Protein Kinase Binding
Protein Binding
Biological Process
Phagocytosis
Lysosome Organization
Protein Localization
Protein Transport
Leukocyte Chemotaxis
Melanosome Organization
Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway
Mast Cell Secretory Granule Organization
Natural Killer Cell Mediated Cytotoxicity
Defense Response To Bacterium
Defense Response To Protozoan
Pigmentation
Defense Response To Virus
Neuron Projection Development
Bone Resorption
Regulation Of Neuronal Synaptic Plasticity
Pathways
Drugs
Diseases
Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS
Basophil percentage of white cells (
32888494
)
Lymphocyte counts (
32888494
)
Monocyte count (
32888494
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Systemic lupus erythematosus (
26502338
19838195
)
Interacting Genes
24 interacting genes:
ATN1
CALM1
CELF4
CENPJ
CNTROB
CSNK2B
DNAJC14
EFS
ESRRA
ESS2
HGS
HNRNPM
KPNB1
MED12
MRPL17
MRPS31
NCDN
PCBP4
TNNI3
VTA1
YWHAB
YWHAQ
YWHAZ
ZNF521
13 interacting genes:
A2M
ACD
EFHC2
KRT75
LYST
PAX6
POT1
PREX1
SEMA4C
TINF2
TLE5
ZBED1
ZNF398
Entrez ID
1130
23154
HPRD ID
06060
10530
Ensembl ID
ENSG00000143669
ENSG00000020129
Uniprot IDs
Q99698
Q9UBB6
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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