PKP3 and DSC1

Data Source:
HPRD (two hybrid)

		PKP3	DSC1
Description		plakophilin 3	desmocollin 1
Image		No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Nucleus Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Cell Junction Desmosome Messenger Ribonucleoprotein Complex	Cornified Envelope Plasma Membrane Cell-cell Junction Gap Junction Membrane Integral Component Of Membrane Desmosome Extracellular Exosome Ficolin-1-rich Granule Membrane
	Molecular Function	RNA Binding Protein Binding Enzyme Binding Translation Regulator Activity Alpha-catenin Binding Cadherin Binding Cell Adhesion Molecule Binding Cadherin Binding Involved In Cell-cell Adhesion	Calcium Ion Binding Protein Binding
	Biological Process	Desmosome Assembly Regulation Of Translation Cell-cell Junction Assembly Positive Regulation Of Gene Expression Keratinization Cornification Protein Localization To Plasma Membrane Cell-cell Adhesion Negative Regulation Of MRNA Catabolic Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Keratinization Neutrophil Degranulation Cornification Cell-cell Adhesion
Pathways		Keratinization Formation of the cornified envelope	Neutrophil degranulation Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Anorectal malformation ( 31136621) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)	Multiple sclerosis ( 23412934)
Interacting Genes		10 interacting genes: DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSP IQUB JUP KRT18	8 interacting genes: DSG1 DSG2 DSP JUP PKP1 PKP2 PKP3 UCHL5
Entrez ID		11187	1823
HPRD ID		05711	00511
Ensembl ID		ENSG00000184363	ENSG00000134765
Uniprot IDs		Q9Y446	Q08554 Q9HB00
PDB IDs			5IRY
Enriched GO Terms of Interacting Partners?
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