PKP3 and DSG1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, two hybrid)

		PKP3	DSG1
Description		plakophilin 3	desmoglein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Nucleus Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Cell Junction Desmosome Messenger Ribonucleoprotein Complex	Cornified Envelope Cytosol Plasma Membrane Cell-cell Junction Cytoplasmic Side Of Plasma Membrane Integral Component Of Membrane Apical Plasma Membrane Lateral Plasma Membrane Desmosome Ficolin-1-rich Granule Membrane
	Molecular Function	RNA Binding Protein Binding Enzyme Binding Translation Regulator Activity Alpha-catenin Binding Cadherin Binding Cell Adhesion Molecule Binding Cadherin Binding Involved In Cell-cell Adhesion	Calcium Ion Binding Protein Binding Toxic Substance Binding Gamma-catenin Binding
	Biological Process	Desmosome Assembly Regulation Of Translation Cell-cell Junction Assembly Positive Regulation Of Gene Expression Keratinization Cornification Protein Localization To Plasma Membrane Cell-cell Adhesion Negative Regulation Of MRNA Catabolic Process	Cell-cell Junction Assembly Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Keratinization Response To Progesterone Neutrophil Degranulation Protein Stabilization Maternal Process Involved In Female Pregnancy Cornification Cell-cell Adhesion
Pathways		Keratinization Formation of the cornified envelope	Apoptotic cleavage of cell adhesion proteins Neutrophil degranulation Keratinization Formation of the cornified envelope
Drugs
Diseases			Striate palmoplantar keratoderma
GWAS		Anorectal malformation ( 31136621) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)	Eosinophilic esophagitis (pediatric) ( 20208534) perceptual and visual search speed (trail making test A) (age interaction) ( 24629169) Yeast infection ( 28928442)
Interacting Genes		10 interacting genes: DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSP IQUB JUP KRT18	8 interacting genes: CDC42 DSC1 DSC2 JUP KLK5 PKP1 PKP2 PKP3
Entrez ID		11187	1828
HPRD ID		05711	00515
Ensembl ID		ENSG00000184363	ENSG00000134760
Uniprot IDs		Q9Y446	Q02413
PDB IDs
Enriched GO Terms of Interacting Partners?
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