PKP3 and DSC3

Data Source:
HPRD (in vivo, two hybrid)

		PKP3	DSC3
Description		plakophilin 3	desmocollin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Nucleus Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Cell Junction Desmosome Messenger Ribonucleoprotein Complex	Cornified Envelope Extracellular Region Cytoplasm Plasma Membrane Cell-cell Junction Membrane Integral Component Of Membrane Cell Junction Desmosome
	Molecular Function	RNA Binding Protein Binding Enzyme Binding Translation Regulator Activity Alpha-catenin Binding Cadherin Binding Cell Adhesion Molecule Binding Cadherin Binding Involved In Cell-cell Adhesion	Calcium Ion Binding Gamma-catenin Binding
	Biological Process	Desmosome Assembly Regulation Of Translation Cell-cell Junction Assembly Positive Regulation Of Gene Expression Keratinization Cornification Protein Localization To Plasma Membrane Cell-cell Adhesion Negative Regulation Of MRNA Catabolic Process	In Utero Embryonic Development Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Keratinization Cornification Cell-cell Adhesion
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases			Hypotrichosis and recurrent skin vesicles
GWAS		Anorectal malformation ( 31136621) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)	Bronchopulmonary dysplasia ( 23897914) Hand grip strength (Mahalanobis distance) ( 32235003) Metabolite levels ( 31628463) Obesity-related traits ( 23251661) Protein quantitative trait loci ( 18464913) Supraventricular ectopy ( 29618737) Type 2 diabetes ( 31049640)
Interacting Genes		10 interacting genes: DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSP IQUB JUP KRT18	5 interacting genes: CTNNB1 JUP PKP3 PKP4 UCHL5
Entrez ID		11187	1825
HPRD ID		05711	02604
Ensembl ID		ENSG00000184363	ENSG00000134762
Uniprot IDs		Q9Y446	Q14574
PDB IDs
Enriched GO Terms of Interacting Partners?
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