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PRSS23 and CHP1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PRSS23
CHP1
Description
serine protease 23
calcineurin like EF-hand protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Endoplasmic Reticulum Lumen
Extracellular Exosome
Golgi Membrane
Nucleus
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum-Golgi Intermediate Compartment
Cytosol
Plasma Membrane
Focal Adhesion
Microtubule Cytoskeleton
Transport Vesicle
Extracellular Exosome
Molecular Function
Serine-type Endopeptidase Activity
Protein Binding
Protein Kinase Inhibitor Activity
Calcium Ion Binding
Protein Binding
Microtubule Binding
Potassium Channel Regulator Activity
Kinase Binding
Calcium-dependent Protein Binding
Biological Process
Proteolysis
Post-translational Protein Modification
Cellular Protein Metabolic Process
Microtubule Bundle Formation
Negative Regulation Of Protein Phosphorylation
Negative Regulation Of Protein Kinase Activity
Protein Export From Nucleus
Potassium Ion Transport
Vesicle Targeting
Vesicle Fusion
Small GTPase Mediated Signal Transduction
Negative Regulation Of Phosphatase Activity
Membrane Docking
Hyaluronan Catabolic Process
Cytoplasmic Microtubule Organization
Negative Regulation Of Protein Ubiquitination
Negative Regulation Of Protein Autophosphorylation
Negative Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Sodium:proton Antiporter Activity
Negative Regulation Of Protein Import Into Nucleus
Protein Stabilization
Positive Regulation Of Protein Transport
Protein Complex Oligomerization
Regulation Of Intracellular PH
Positive Regulation Of Protein Glycosylation
Membrane Organization
Membrane Fusion
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Positive Regulation Of Phospholipid Biosynthetic Process
Cellular Response To Acidic PH
Positive Regulation Of Protein Targeting To Membrane
Regulation Of Neuron Death
Pathways
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Hyaluronan uptake and degradation
Drugs
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Diseases
GWAS
Blood urea nitrogen levels (
31152163
)
Chronic obstructive pulmonary disease (
30804561
)
FEV1 (
30804560
)
Heel bone mineral density (
30598549
28869591
)
Intraocular pressure (
29617998
29785010
)
Lung function (FEV1) (
28166213
)
Lung function (FEV1/FVC) (
30804560
)
Peak expiratory flow (
30804560
)
Allergic disease (asthma, hay fever or eczema) (
29785011
)
Essential hypertension (time to event) (
32589924
)
Estimated glomerular filtration rate (
31015462
)
Ulcerative colitis (
28067908
)
White blood cell count (
32888494
)
Interacting Genes
26 interacting genes:
ACTG1
APP
B2M
CHP1
EFNA3
FXR1
GATD1
GRK6
HSPA4
MAPK8IP2
NCAPD3
NIPBL
NOC4L
ODF2L
PDPK1
PHF23
PPIA
RACGAP1
RECQL4
RPL4P5
SEC11C
SHMT1
SLC25A6
TCF12
TMEM222
TRAPPC4
10 interacting genes:
GAPDH
KIF1B
PRSS23
SLC9A1
SLC9A2
SLC9A3
SLC9A4
SLC9A5
STK17B
UBC
Entrez ID
11098
11261
HPRD ID
07149
06101
Ensembl ID
ENSG00000150687
ENSG00000187446
Uniprot IDs
O95084
A0A024R9M9
H0YKE7
Q99653
PDB IDs
2E30
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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