CHP1 and STK17B

Data Source:
HPRD (in vitro)

		CHP1	STK17B
Description		calcineurin like EF-hand protein 1	serine/threonine kinase 17b
Image
GO Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Plasma Membrane Focal Adhesion Microtubule Cytoskeleton Transport Vesicle Extracellular Exosome	Nucleus Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane Actin Cytoskeleton
	Molecular Function	Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Microtubule Binding Potassium Channel Regulator Activity Kinase Binding Calcium-dependent Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Microtubule Bundle Formation Negative Regulation Of Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Protein Export From Nucleus Potassium Ion Transport Vesicle Targeting Vesicle Fusion Small GTPase Mediated Signal Transduction Negative Regulation Of Phosphatase Activity Membrane Docking Hyaluronan Catabolic Process Cytoplasmic Microtubule Organization Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Autophosphorylation Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Protein Import Into Nucleus Protein Stabilization Positive Regulation Of Protein Transport Protein Complex Oligomerization Regulation Of Intracellular PH Positive Regulation Of Protein Glycosylation Membrane Organization Membrane Fusion Negative Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Phospholipid Biosynthetic Process Cellular Response To Acidic PH Positive Regulation Of Protein Targeting To Membrane Regulation Of Neuron Death	Protein Phosphorylation Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Protein Autophosphorylation Positive Regulation Of Fibroblast Apoptotic Process
Pathways		Hyaluronan uptake and degradation
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate	Quercetin Fostamatinib
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Essential hypertension (time to event) ( 32589924) Estimated glomerular filtration rate ( 31015462) Ulcerative colitis ( 28067908) White blood cell count ( 32888494)	Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		10 interacting genes: GAPDH KIF1B PRSS23 SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5 STK17B UBC	3 interacting genes: APP CHP1 RPS24
Entrez ID		11261	9262
HPRD ID		06101	05289
Ensembl ID		ENSG00000187446	ENSG00000081320
Uniprot IDs		A0A024R9M9 H0YKE7 Q99653	O94768 Q53QE7
PDB IDs		2E30	3LM0 3LM5 6QF4 6Y6F 6Y6H 6ZJF
Enriched GO Terms of Interacting Partners?
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