CHP1 and SLC9A4

Data Source:
HPRD (in vivo, in vitro)

		CHP1	SLC9A4
Description		calcineurin like EF-hand protein 1	solute carrier family 9 member A4
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Plasma Membrane Focal Adhesion Microtubule Cytoskeleton Transport Vesicle Extracellular Exosome	Vacuolar Membrane Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Microtubule Binding Potassium Channel Regulator Activity Kinase Binding Calcium-dependent Protein Binding	Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity
	Biological Process	Microtubule Bundle Formation Negative Regulation Of Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Protein Export From Nucleus Potassium Ion Transport Vesicle Targeting Vesicle Fusion Small GTPase Mediated Signal Transduction Negative Regulation Of Phosphatase Activity Membrane Docking Hyaluronan Catabolic Process Cytoplasmic Microtubule Organization Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Autophosphorylation Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Protein Import Into Nucleus Protein Stabilization Positive Regulation Of Protein Transport Protein Complex Oligomerization Regulation Of Intracellular PH Positive Regulation Of Protein Glycosylation Membrane Organization Membrane Fusion Negative Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Phospholipid Biosynthetic Process Cellular Response To Acidic PH Positive Regulation Of Protein Targeting To Membrane Regulation Of Neuron Death	Gastric Acid Secretion Epithelial Cell Development Ion Transport Response To Salt Stress Regulation Of Intracellular PH Potassium Ion Homeostasis Potassium Ion Transmembrane Transport Anion Transmembrane Transport Sodium Ion Import Across Plasma Membrane Proton Transmembrane Transport
Pathways		Hyaluronan uptake and degradation	Sodium/Proton exchangers
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Essential hypertension (time to event) ( 32589924) Estimated glomerular filtration rate ( 31015462) Ulcerative colitis ( 28067908) White blood cell count ( 32888494)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Basophil count ( 32888494) Bisphosphonate-associated atypical femoral fracture ( 31006051) Blood protein levels ( 28240269) Celiac disease ( 25920553 30572963 18311140) Crohn's disease ( 28067908) Delirium ( 29631748) Estimated glomerular filtration rate ( 31152163) Inflammatory bowel disease ( 28067908) Lymphocyte counts ( 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Night sleep phenotypes ( 27126917) Serum protein levels (sST2) ( 23999434) White blood cell types ( 21738478)
Interacting Genes		10 interacting genes: GAPDH KIF1B PRSS23 SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5 STK17B UBC	2 interacting genes: CHP1 CHP2
Entrez ID		11261	389015
HPRD ID		06101	15973
Ensembl ID		ENSG00000187446	ENSG00000180251
Uniprot IDs		A0A024R9M9 H0YKE7 Q99653	Q6AI14
PDB IDs		2E30
Enriched GO Terms of Interacting Partners?
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