PRSS23 and NOC4L

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PRSS23	NOC4L
Description		serine protease 23	nucleolar complex associated 4 homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Lumen Extracellular Exosome	Nucleoplasm Nucleolus Integral Component Of Membrane Noc4p-Nop14p Complex Nuclear Membrane Small-subunit Processome
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding	RNA Binding Protein Binding
	Biological Process	Proteolysis Post-translational Protein Modification Cellular Protein Metabolic Process	RRNA Processing
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Chronic obstructive pulmonary disease ( 30804561) FEV1 ( 30804560) Heel bone mineral density ( 30598549 28869591) Intraocular pressure ( 29617998 29785010) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560)	Body mass index ( 26426971) Hirschsprung disease ( 26887379) Response to antidepressants (symptom improvement) ( 29160301) Response to SSRI (symptom remission) ( 29160301)
Interacting Genes		26 interacting genes: ACTG1 APP B2M CHP1 EFNA3 FXR1 GATD1 GRK6 HSPA4 MAPK8IP2 NCAPD3 NIPBL NOC4L ODF2L PDPK1 PHF23 PPIA RACGAP1 RECQL4 RPL4P5 SEC11C SHMT1 SLC25A6 TCF12 TMEM222 TRAPPC4	22 interacting genes: BHLHE40 DAZAP2 DNAJA3 DUSP29 EPM2AIP1 IKZF1 KRT15 KRTAP19-6 LINC00839 LNPK NECAB2 NT5C2 OXER1 PICK1 PLSCR1 PRSS23 TSC22D4 UBQLN2 USHBP1 VIM ZBTB42 ZNRD2
Entrez ID		11098	79050
HPRD ID		07149	14543
Ensembl ID		ENSG00000150687	ENSG00000184967
Uniprot IDs		O95084	Q9BVI4
PDB IDs
Enriched GO Terms of Interacting Partners?
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