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PRSS23 and NIPBL
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PRSS23
NIPBL
Description
serine protease 23
NIPBL cohesin loading factor
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Endoplasmic Reticulum Lumen
Extracellular Exosome
Nucleus
Nucleoplasm
Cytosol
Integrator Complex
SMC Loading Complex
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Scc2-Scc4 Cohesin Loading Complex
Molecular Function
Serine-type Endopeptidase Activity
Protein Binding
Chromatin Binding
Protein Binding
Protein C-terminus Binding
Mediator Complex Binding
Histone Deacetylase Binding
Protein N-terminus Binding
Chromo Shadow Domain Binding
Promoter-specific Chromatin Binding
Biological Process
Proteolysis
Post-translational Protein Modification
Cellular Protein Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Metanephros Development
Heart Morphogenesis
Outflow Tract Morphogenesis
Cellular Response To DNA Damage Stimulus
Mitotic Sister Chromatid Cohesion
Brain Development
Sensory Perception Of Sound
Stem Cell Population Maintenance
Positive Regulation Of Histone Deacetylation
Establishment Of Mitotic Sister Chromatid Cohesion
Maintenance Of Mitotic Sister Chromatid Cohesion
Cellular Protein Localization
Embryonic Forelimb Morphogenesis
Forelimb Morphogenesis
External Genitalia Morphogenesis
Positive Regulation Of Multicellular Organism Growth
Ear Morphogenesis
Regulation Of Hair Cycle
Fat Cell Differentiation
Positive Regulation Of Ossification
Negative Regulation Of Transcription, DNA-templated
Regulation Of Embryonic Development
Embryonic Digestive Tract Morphogenesis
Digestive Tract Development
Developmental Growth
Eye Morphogenesis
Regulation Of Developmental Growth
Embryonic Viscerocranium Morphogenesis
Cognition
Face Morphogenesis
Gall Bladder Development
Uterus Morphogenesis
Establishment Of Protein Localization To Chromatin
Cellular Response To X-ray
Transcriptional Activation By Promoter-enhancer Looping
Cohesin Loading
Positive Regulation Of Mitotic Cohesin Loading
Replication-born Double-strand Break Repair Via Sister Chromatid Exchange
Positive Regulation Of Neuron Migration
Pathways
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Cohesin Loading onto Chromatin
Drugs
Diseases
Cornelia de Lange syndrome (CdLS)
GWAS
Blood urea nitrogen levels (
31152163
)
Chronic obstructive pulmonary disease (
30804561
)
FEV1 (
30804560
)
Heel bone mineral density (
30598549
28869591
)
Intraocular pressure (
29617998
29785010
)
Lung function (FEV1) (
28166213
)
Lung function (FEV1/FVC) (
30804560
)
Peak expiratory flow (
30804560
)
Height (
28552196
25282103
31562340
)
Malaria (
31844061
)
Meat-related diet (
32066663
)
Obesity-related traits (
23251661
)
Weight (
28552196
)
Interacting Genes
26 interacting genes:
ACTG1
APP
B2M
CHP1
EFNA3
FXR1
GATD1
GRK6
HSPA4
MAPK8IP2
NCAPD3
NIPBL
NOC4L
ODF2L
PDPK1
PHF23
PPIA
RACGAP1
RECQL4
RPL4P5
SEC11C
SHMT1
SLC25A6
TCF12
TMEM222
TRAPPC4
7 interacting genes:
CBX5
CDK6
DBN1
HINFP
PRSS23
SP100
SUMO2
Entrez ID
11098
25836
HPRD ID
07149
10560
Ensembl ID
ENSG00000150687
ENSG00000164190
Uniprot IDs
O95084
A0A590UJS4
Q6KC79
PDB IDs
6WG3
6WGE
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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