EHD1 and MICAL1

Data Source:
BioGRID (two hybrid, two hybrid)

		EHD1	MICAL1
Description		EH domain containing 1	microtubule associated monooxygenase, calponin and LIM domain containing 1
Image
GO Annotations	Cellular Component	Cytoplasm Early Endosome Lipid Droplet Plasma Membrane Endosome Membrane Membrane Ciliary Pocket Membrane Endocytic Vesicle Platelet Dense Tubular Network Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome	Cytoplasm Cytosol Intermediate Filament Plasma Membrane Actin Cytoskeleton Midbody Intercellular Bridge Hippocampal Mossy Fiber Expansion
	Molecular Function	Calcium Ion Binding Protein Binding ATP Binding GTP Binding Small GTPase Binding Identical Protein Binding Cadherin Binding	Actin Binding Protein Binding NAD(P)H Oxidase H2O2-forming Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen SH3 Domain Binding Protein Kinase Binding Small GTPase Binding Metal Ion Binding Actin Filament Binding FAD Binding
	Biological Process	Intracellular Protein Transport Endocytosis Blood Coagulation Positive Regulation Of Cholesterol Storage Endosomal Transport Neuron Projection Development Endocytic Recycling Low-density Lipoprotein Particle Clearance Cholesterol Homeostasis Protein Homooligomerization Cilium Assembly Protein Localization To Cilium Protein Localization To Plasma Membrane Positive Regulation Of Myoblast Fusion Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Endocytic Recycling	Negative Regulation Of Protein Phosphorylation Cytoskeleton Organization Signal Transduction Blood Coagulation Sulfur Oxidation Actin Filament Depolymerization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Actin Filament Bundle Assembly Regulation Of Regulated Secretory Pathway
Pathways		Factors involved in megakaryocyte development and platelet production	Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Depression in smokers ( 30219690) Height ( 28552196)
Interacting Genes		13 interacting genes: ANKFY1 AP2A1 EHBP1 EHD3 HSPB1 IGF1R MICAL1 MICALL1 MUL1 RAB11FIP2 RBSN RFFL SNAP29	16 interacting genes: ABL1 CRK EHD1 GADD45A GRB2 GSK3B NEDD9 PIK3R3 PTK2 RAB10 RAB1A RAB1B RPS6KA6 SRC TAB1 VIM
Entrez ID		10938	64780
HPRD ID		09325	06183
Ensembl ID		ENSG00000110047	ENSG00000135596
Uniprot IDs		A0A024R571 B2R5U3 Q9H4M9	Q8TDZ2
PDB IDs		2JQ6 2KFF 2KFG 2KFH 2KSP	1WYL 2CO8 2DK9 5LE0 5LPN 6KU0
Enriched GO Terms of Interacting Partners?
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