RUNDC3A and HTR6

Data Source:
BioGRID (two hybrid)

		RUNDC3A	HTR6
Description		RUN domain containing 3A	5-hydroxytryptamine receptor 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Intracellular Membrane-bounded Organelle	Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendrite Synapse
	Molecular Function	Protein Binding GTPase Regulator Activity	Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of CGMP-mediated Signaling Regulation Of Catalytic Activity	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Cerebral Cortex Cell Migration Positive Regulation Of TOR Signaling G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways			Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Ziprasidone Amitriptyline Olanzapine Clozapine Loxapine Imipramine Chlorpromazine Haloperidol Amoxapine Paroxetine Cyclobenzaprine Ergoloid mesylate Doxepin Quetiapine Aripiprazole Chlorprothixene Dimethyltryptamine Lysergic acid diethylamide Iloperidone SGS518 PRX-07034 SUVN-502 Sertindole Mianserin Asenapine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS			Chronotype ( 26955885 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 27494321)
Interacting Genes		35 interacting genes: AP1M1 AP2M1 ARMC7 CCNL2 DDX6 EIF3E ENKD1 FAM161A GEM GFI1B HTR6 LNX1 MAGEB4 MAGOHB MBD3L2 MRPL15 MYO15B PRPF31 RAP1A RAP2A RAP2B SDCBP SYT17 TBRG1 TEAD4 TFPT TSGA10IP TSHR UBTFL1 USP2 ZNF250 ZNF417 ZNF587 ZNF821 ZNF835	31 interacting genes: ABCA2 ACTB AIP AKR1A1 AP2M1 AP4S1 ATXN10 CHN1 CMSS1 COPS5 DDRGK1 DHRS1 EIF4A3 FYN GNAQ GNAS HDGFL2 IDS MAP1B NF1 NRXN3 PARP8 RUNDC3A SCHIP1 SLC6A1 SRRT SYT5 THY1 TMEM98 TTYH1 UQCRFS1
Entrez ID		10900	3362
HPRD ID		16106	03066
Ensembl ID		ENSG00000108309	ENSG00000158748
Uniprot IDs		Q59EK9	P50406
PDB IDs
Enriched GO Terms of Interacting Partners?
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