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NEK6 and LZTS2
Data Source:
BioGRID
(two hybrid)
NEK6
LZTS2
Description
NIMA related kinase 6
leucine zipper tumor suppressor 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Spindle Pole
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Microtubule
Nuclear Speck
Protein-containing Complex
Centriolar Satellite
Centrosome
Cytosol
Microtubule
Plasma Membrane
Midbody
Vesicle
Molecular Function
Magnesium Ion Binding
Transcription Corepressor Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Kinesin Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Activating Transcription Factor Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Protein Binding
Biological Process
Protein Phosphorylation
Apoptotic Process
Chromosome Segregation
Mitotic Nuclear Envelope Disassembly
Regulation Of Mitotic Cell Cycle
Peptidyl-serine Phosphorylation
Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Protein Autophosphorylation
Spindle Assembly
Cell Division
Regulation Of Cellular Senescence
Mitotic Cytokinesis
Negative Regulation Of Cell Population Proliferation
Wnt Signaling Pathway
Microtubule Severing
Nuclear Export
Spindle Midzone Assembly
Primary Ureteric Bud Growth
Ureter Morphogenesis
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Pathways
Activation of NIMA Kinases NEK9, NEK6, NEK7
Nuclear Pore Complex (NPC) Disassembly
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Asthma (
32296059
)
Asthma exacerbations in inhaled corticosteroid treatment (
30697902
)
Blond vs. brown/black hair color (
30531825
)
Chronotype (
30696823
)
Cognitive performance (
20125193
)
Free thyroxine concentration (
30367059
)
Heel bone mineral density (
30598549
)
Medication use (thyroid preparations) (
31015401
)
Mercury levels (
26025379
)
Neurociticism (
29500382
)
Pulse pressure (
30224653
)
Thyroid stimulating hormone levels (
32769997
)
Vitiligo (
27723757
)
Ejection fraction in Tripanosoma cruzi seropositivity (
24324551
)
Regular attendance at a pub or social club (
29970889
)
Interacting Genes
117 interacting genes:
ANKRA2
ARHGAP33
ARRB1
ATF4
BEND7
BHLHE40
CBY2
CCDC120
CCDC136
CCDC85B
CDC42
CDK7
CEP76
CFP
CIR1
COG6
CTBP2
DDIT4L
DES
DPH2
EFHC2
ERCC6L2
FAM220A
FHL5
FOXJ3
GFAP
GIGYF1
GLIS3
GOLGA6L2
GRIP1
HOMEZ
HOOK2
HOXA1
HOXB6
HSD17B14
IHO1
IKZF1
IKZF3
INCA1
KATNBL1
KCTD5
KIAA1328
KRT31
KRT34
KRT40
KRT75
KRT8
KRTAP10-8
KRTAP13-1
KRTAP13-3
LNX1
LZTS1
LZTS2
MBD3L1
MEOX2
METTL15
MYOG
MYOZ3
NECAB2
NEFL
NEK9
NIF3L1
NUDT16L1
PAK6
PBX4
PHF1
PICK1
PIN1
PLEKHA7
PPP1R16A
PRAM1
PRDM16
PRDM6
PRDX3
PRICKLE4
PTN
PTPN21
PTPRD
RBAK
RBBP6
RIMBP3C
RPS6KB1
RPS7
SAXO1
SGK1
SH3RF2
SMAD4
SMUG1
SMURF2
SORBS3
SPRY3
TASOR2
TCF12
TCF4
TEPSIN
TEX45
TFIP11
TGFBR1
TLE5
TNK2
TRAF2
TRIM23
TRIM27
TRIM54
TRIP4
UBXN11
XIAP
ZC2HC1C
ZCCHC7
ZFP90
ZNF24
ZNF343
ZNF438
ZNF587
ZNF688
ZNF774
ZRANB1
217 interacting genes:
ABI2
ABT1
AEN
ANKRD11
ANKRD36BP1
AP1M1
ARMC7
ARNT2
ATPAF2
BAHD1
BEX2
BMS1P1
BYSL
C1orf109
C2CD6
C8orf33
CABP5
CARD9
CATSPER1
CBX8
CCDC187
CCDC198
CCDC85B
CCNC
CCNG1
CCNK
CDC23
CDK18
CDKL3
CDKN1A
CEP57L1
CFAP206
CHCHD3
CHIC2
CLIP4
CNNM3
COPB1
CSNK1D
CWF19L2
DCUN1D1
DGCR6
DGCR6L
DUSP4
DYRK2
EHHADH
EIF3D
EIF4E2
EXOSC5
FAM107A
FAM124B
FAM161A
FAM214B
FAM221B
FAM50B
FAM74A4
FAM90A1
FANCL
FEM1C
FGF12
FKBP6
FNDC11
FRG1
FRMD6
GADD45GIP1
GATA1
GCC1
GEM
GFI1B
GIPC2
GLIDR
GLYCTK
GMCL2
GNL3L
GPANK1
GPATCH2L
GRB2
HLA-DPB1
HM13
HOMER2
HOXB9
HSPD1
IGFN1
INO80B
IQCE
IQCN
KAT5
KAZN
KIF9
KIFC3
KPNA2
LASP1
LCK
LIN37
LMO1
LMO2
LMO3
MAB21L3
MAGEB4
MAPK1
MEMO1
MID2
MORF4L1
MORF4L2
MORN3
MOS
MTA1
MYOZ1
NCBP2
NCK2
NDE1
NEBL
NEK6
NINL
NIP7
NTAQ1
OTUB2
PAK5
PATZ1
PHF1
PHF19
PITX1
PKP4
PLEKHN1
POLDIP3
POLR1C
PPP1R16A
PPP1R18
PQBP1
PRKAA2
PRKAB2
PRPF18
PRPF31
PRR35
PSMA1
QARS1
RAC1
RAD51D
RAMAC
RBFOX1
RBM15
RBM41
RBPMS
RCOR3
RHNO1
RHOXF2
RIN1
RNF32
RNF41
RTP5
RUNX1T1
SCNM1
SH2D4A
SH3KBP1
SH3RF2
SHFL
SLC15A3
SLC25A6
SLC39A14
SLU7
SMARCB1
SMARCD1
SMIM3
SNHG11
SNW1
SNX31
SPATA24
SPATC1L
SPG7
SRSF2
STAC
SUPV3L1
SUV39H1
SYT17
TBC1D7
TCEA2
TEAD4
THAP10
THAP7
TLE5
TNIP3
TRAF2
TRIM29
TRIM42
TSNAX
TSSK2
TSSK3
TTC23
TTLL10
TXNL4A
UBASH3A
UBASH3B
USF2
USP2
UTP14C
VEZF1
WT1-AS
YTHDC1
ZBTB25
ZBTB38
ZC2HC1C
ZGPAT
ZKSCAN3
ZMAT1
ZMAT2
ZMYND19
ZNF124
ZNF20
ZNF250
ZNF408
ZNF417
ZNF426
ZNF446
ZNF490
ZNF512B
ZNF572
ZNF581
ZNF648
Entrez ID
10783
84445
HPRD ID
05348
14341
Ensembl ID
ENSG00000119408
ENSG00000107816
Uniprot IDs
A0A024R8A6
Q9HC98
B4DP66
Q9BRK4
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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