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LZTS2 and ABI2
Data Source:
BioGRID
(two hybrid)
LZTS2
ABI2
Description
leucine zipper tumor suppressor 2
abl interactor 2
Image
No pdb structure
GO Annotations
Cellular Component
Centrosome
Cytosol
Microtubule
Plasma Membrane
Midbody
Vesicle
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Adherens Junction
Lamellipodium
SCAR Complex
Filopodium Tip
Dendritic Spine
Molecular Function
Protein Binding
Protein Binding
Cytoskeletal Anchor Activity
SH3 Domain Binding
Kinase Binding
Small GTPase Binding
Ubiquitin Protein Ligase Binding
Signaling Adaptor Activity
Identical Protein Binding
Proline-rich Region Binding
Biological Process
Mitotic Cytokinesis
Negative Regulation Of Cell Population Proliferation
Wnt Signaling Pathway
Microtubule Severing
Nuclear Export
Spindle Midzone Assembly
Primary Ureteric Bud Growth
Ureter Morphogenesis
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Cytoskeleton Organization
Nervous System Development
Actin Polymerization Or Depolymerization
Positive Regulation Of Lamellipodium Assembly
Viral Process
Cell Migration
Rac Protein Signal Transduction
Peptidyl-tyrosine Phosphorylation
Regulation Of Dendritic Spine Morphogenesis
Lens Fiber Cell Morphogenesis
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Ejection fraction in Tripanosoma cruzi seropositivity (
24324551
)
Regular attendance at a pub or social club (
29970889
)
Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) (
28090653
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Butyrylcholinesterase levels (
21862451
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Diverticular disease (
30177863
)
Subclinical atherosclerosis traits (other) (
17903303
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Trunk fat mass (
28552196
)
Urinary albumin-to-creatinine ratio (
31511532
)
Interacting Genes
217 interacting genes:
ABI2
ABT1
AEN
ANKRD11
ANKRD36BP1
AP1M1
ARMC7
ARNT2
ATPAF2
BAHD1
BEX2
BMS1P1
BYSL
C1orf109
C2CD6
C8orf33
CABP5
CARD9
CATSPER1
CBX8
CCDC187
CCDC198
CCDC85B
CCNC
CCNG1
CCNK
CDC23
CDK18
CDKL3
CDKN1A
CEP57L1
CFAP206
CHCHD3
CHIC2
CLIP4
CNNM3
COPB1
CSNK1D
CWF19L2
DCUN1D1
DGCR6
DGCR6L
DUSP4
DYRK2
EHHADH
EIF3D
EIF4E2
EXOSC5
FAM107A
FAM124B
FAM161A
FAM214B
FAM221B
FAM50B
FAM74A4
FAM90A1
FANCL
FEM1C
FGF12
FKBP6
FNDC11
FRG1
FRMD6
GADD45GIP1
GATA1
GCC1
GEM
GFI1B
GIPC2
GLIDR
GLYCTK
GMCL2
GNL3L
GPANK1
GPATCH2L
GRB2
HLA-DPB1
HM13
HOMER2
HOXB9
HSPD1
IGFN1
INO80B
IQCE
IQCN
KAT5
KAZN
KIF9
KIFC3
KPNA2
LASP1
LCK
LIN37
LMO1
LMO2
LMO3
MAB21L3
MAGEB4
MAPK1
MEMO1
MID2
MORF4L1
MORF4L2
MORN3
MOS
MTA1
MYOZ1
NCBP2
NCK2
NDE1
NEBL
NEK6
NINL
NIP7
NTAQ1
OTUB2
PAK5
PATZ1
PHF1
PHF19
PITX1
PKP4
PLEKHN1
POLDIP3
POLR1C
PPP1R16A
PPP1R18
PQBP1
PRKAA2
PRKAB2
PRPF18
PRPF31
PRR35
PSMA1
QARS1
RAC1
RAD51D
RAMAC
RBFOX1
RBM15
RBM41
RBPMS
RCOR3
RHNO1
RHOXF2
RIN1
RNF32
RNF41
RTP5
RUNX1T1
SCNM1
SH2D4A
SH3KBP1
SH3RF2
SHFL
SLC15A3
SLC25A6
SLC39A14
SLU7
SMARCB1
SMARCD1
SMIM3
SNHG11
SNW1
SNX31
SPATA24
SPATC1L
SPG7
SRSF2
STAC
SUPV3L1
SUV39H1
SYT17
TBC1D7
TCEA2
TEAD4
THAP10
THAP7
TLE5
TNIP3
TRAF2
TRIM29
TRIM42
TSNAX
TSSK2
TSSK3
TTC23
TTLL10
TXNL4A
UBASH3A
UBASH3B
USF2
USP2
UTP14C
VEZF1
WT1-AS
YTHDC1
ZBTB25
ZBTB38
ZC2HC1C
ZGPAT
ZKSCAN3
ZMAT1
ZMAT2
ZMYND19
ZNF124
ZNF20
ZNF250
ZNF408
ZNF417
ZNF426
ZNF446
ZNF490
ZNF512B
ZNF572
ZNF581
ZNF648
197 interacting genes:
ABI1
ABI3
ABL1
ABL2
ABLIM3
ADAM19
AKAP8L
AKAP9
ANKRD55
ANKS1A
ARHGAP32
ARMC7
ATP23
BAG4
BIN3
BLOC1S5
BLOC1S6
BORCS6
C19orf54
C1orf109
C1orf216
C20orf202
C4orf17
CCDC102B
CCDC115
CCDC57
CCDC74B
CCHCR1
CDK6
CENPH
CENPQ
CEP44
CEP57
CLPP
COG3
CRX
CUEDC1
DCTN2
DISC1
DLGAP2
DLGAP4
DNAI7
DTNB
EFS
EGLN3
EGR4
EIF3H
ENAH
ENKD1
EPS8L1
FAM161B
FAM166B
FAM214B
FAM90A1
FAM9C
FBXL19
FHL5
FKBP1A
FOXD4L1
GAS2L2
GCC1
GFAP
GGN
GPANK1
HGS
HHEX
HNRNPK
HOMER3
HSF2BP
IFT20
IHO1
INCA1
INO80B
INSYN1
KHDRBS1
KIAA1217
KIFC3
KNSTRN
KRT13
KRT14
KRT15
KRT19
KRT20
KRT24
KRT27
KRT31
KRT33B
KRT34
KRT36
KRT75
LENG1
LGALS9B
LHX3
LHX8
LMO1
LMO2
LMO3
LMO4
LNX1
LURAP1
LZTS2
MAGEA1
MCM7
MED10
MED11
MED29
MEOX2
MRFAP1
MRFAP1L1
MRPL28
MRPL44
MYO15B
MYOG
MYOZ3
NCK1
NCK2
NCKIPSD
NFASC
NHSL2
NME4
NUP62
OIP5
OOEP
PAK2
PCM1
PDLIM7
PFDN5
PHETA1
PHF1
PIN1
PLEKHN1
POMC
PPIF
PPP3CA
PRAM1
PRDM14
PRDM6
PRKAA1
PRKAA2
PRR16
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSMA1
PWWP2B
RABEP1
RABGEF1
RASD1
RNPS1
RPP25
RSPH14
RUSC1
SCGN
SDCBP
SH3BP1
SH3KBP1
SLA
SMARCB1
SMARCD1
SNAP23
SNAP91
SNAPIN
SNX18
SNX7
SORBS3
STAM2
STX19
STX4
TFIP11
TLE5
TPM2
TRAF3IP1
TRIM32
TRIM72
TRIML2
TRIP6
UBQLN2
USHBP1
USP2
VARS2
VASP
VCL
VPS28
VPS37C
WASF2
WASF3
WASHC1
WASHC3
WASL
WIPF1
WWOX
ZFP90
ZMYND12
ZNF474
ZNF688
Entrez ID
84445
10152
HPRD ID
14341
07338
Ensembl ID
ENSG00000107816
ENSG00000138443
Uniprot IDs
B4DP66
Q9BRK4
A0A0C4DG21
A0A7D9NKC8
B7Z836
F8WAL6
Q9NYB9
PDB IDs
2ED0
3P8C
4N78
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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