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NEK6 and TEPSIN
Data Source:
BioGRID
(two hybrid)
NEK6
TEPSIN
Description
NIMA related kinase 6
TEPSIN adaptor related protein complex 4 accessory protein
Image
No pdb structure
GO Annotations
Cellular Component
Spindle Pole
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Microtubule
Nuclear Speck
Protein-containing Complex
Centriolar Satellite
Cytoplasm
Golgi Apparatus
Cytosol
Nuclear Speck
AP-4 Adaptor Complex
Coated Vesicle Membrane
Extrinsic Component Of Organelle Membrane
Nuclear Membrane
Trans-Golgi Network Membrane
Molecular Function
Magnesium Ion Binding
Transcription Corepressor Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Kinesin Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Activating Transcription Factor Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Protein Binding
Biological Process
Protein Phosphorylation
Apoptotic Process
Chromosome Segregation
Mitotic Nuclear Envelope Disassembly
Regulation Of Mitotic Cell Cycle
Peptidyl-serine Phosphorylation
Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Protein Autophosphorylation
Spindle Assembly
Cell Division
Regulation Of Cellular Senescence
Pathways
Activation of NIMA Kinases NEK9, NEK6, NEK7
Nuclear Pore Complex (NPC) Disassembly
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Asthma (
32296059
)
Asthma exacerbations in inhaled corticosteroid treatment (
30697902
)
Blond vs. brown/black hair color (
30531825
)
Chronotype (
30696823
)
Cognitive performance (
20125193
)
Free thyroxine concentration (
30367059
)
Heel bone mineral density (
30598549
)
Medication use (thyroid preparations) (
31015401
)
Mercury levels (
26025379
)
Neurociticism (
29500382
)
Pulse pressure (
30224653
)
Thyroid stimulating hormone levels (
32769997
)
Vitiligo (
27723757
)
IgG N-glycosylation phenotypes (multivariate analysis) (
32128391
)
Interacting Genes
117 interacting genes:
ANKRA2
ARHGAP33
ARRB1
ATF4
BEND7
BHLHE40
CBY2
CCDC120
CCDC136
CCDC85B
CDC42
CDK7
CEP76
CFP
CIR1
COG6
CTBP2
DDIT4L
DES
DPH2
EFHC2
ERCC6L2
FAM220A
FHL5
FOXJ3
GFAP
GIGYF1
GLIS3
GOLGA6L2
GRIP1
HOMEZ
HOOK2
HOXA1
HOXB6
HSD17B14
IHO1
IKZF1
IKZF3
INCA1
KATNBL1
KCTD5
KIAA1328
KRT31
KRT34
KRT40
KRT75
KRT8
KRTAP10-8
KRTAP13-1
KRTAP13-3
LNX1
LZTS1
LZTS2
MBD3L1
MEOX2
METTL15
MYOG
MYOZ3
NECAB2
NEFL
NEK9
NIF3L1
NUDT16L1
PAK6
PBX4
PHF1
PICK1
PIN1
PLEKHA7
PPP1R16A
PRAM1
PRDM16
PRDM6
PRDX3
PRICKLE4
PTN
PTPN21
PTPRD
RBAK
RBBP6
RIMBP3C
RPS6KB1
RPS7
SAXO1
SGK1
SH3RF2
SMAD4
SMUG1
SMURF2
SORBS3
SPRY3
TASOR2
TCF12
TCF4
TEPSIN
TEX45
TFIP11
TGFBR1
TLE5
TNK2
TRAF2
TRIM23
TRIM27
TRIM54
TRIP4
UBXN11
XIAP
ZC2HC1C
ZCCHC7
ZFP90
ZNF24
ZNF343
ZNF438
ZNF587
ZNF688
ZNF774
ZRANB1
127 interacting genes:
AATK
ACBD7
AGRN
AP1M1
AP4B1
APOL6
APP
ASAP3
ASB3
BCL2L14
BCL2L15
BHLHB9
BIRC7
BPIFA1
BTBD3
C1orf109
C1QTNF4
CBX8
CCDC146
CCNC
CDC23
CINP
CLCNKA
CLIC3
CNTF
CPNE7
CSNK2A1
CTAG1A
CTAG1B
CYSRT1
DEF6
DUSP29
DUSP4
DZIP1L
EIF1AD
FAM214B
FAM90A1
FARS2
FKBP6
FLACC1
FNDC3B
GNG13
GOLGA2
GPANK1
GRB10
GRIPAP1
GUCD1
HAT1
HCK
HPCA
HSF2BP
HSPB7
IL16
IQGAP1
KCTD6
KCTD9
KHNYN
KLHL38
KRT31
KRT34
KRT35
KRTAP6-2
LENG1
LGALS14
LMO3
LSM3
LYG2
MAT2B
MED18
MFAP1
MLX
MORF4L1
MSGN1
MTUS2
NDOR1
NEK6
NGB
NME7
NR2C2AP
NTAQ1
NUDT14
NUDT21
OAZ3
OR6B1
PAX9
PCDHB3
PLEKHA2
PSMA6
RAB3IP
RAD51D
RANBP3
RNF135
SEC14L4
SLU7
SNRNP25
SORBS2
SORBS3
SZT2
TAPBPL
TBC1D13
TBC1D22B
TCEA2
TCL1A
TFAP2D
THRSP
TRAPPC2
TRAPPC2B
TRAPPC6A
TRIM23
TRIM45
TRIM50
TRIM54
TRIM68
TSEN15
TSEN2
TSHZ3
TSSK3
UBASH3B
UTP23
VPS26C
WDR25
YPEL3
ZIC1
ZMYND12
ZNF343
ZNF629
ZRSR2
Entrez ID
10783
146705
HPRD ID
05348
08103
Ensembl ID
ENSG00000119408
ENSG00000167302
Uniprot IDs
A0A024R8A6
Q9HC98
Q96N21
PDB IDs
5WF9
5WFB
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Difference)
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Tagcloud (Intersection)
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