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RGS7 and CHRM1
Data Source:
BioGRID
(pull down)
RGS7
CHRM1
Description
regulator of G protein signaling 7
cholinergic receptor muscarinic 1
Image
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Dendrite
Axon Terminus
Synapse
Schaffer Collateral - CA1 Synapse
Glutamatergic Synapse
Cholinergic Synapse
Integral Component Of Presynaptic Membrane
Integral Component Of Postsynaptic Density Membrane
Molecular Function
GTPase Activity
GTPase Activator Activity
G-protein Beta-subunit Binding
Phosphatidylinositol Phospholipase C Activity
G Protein-coupled Serotonin Receptor Activity
Protein Binding
G Protein-coupled Acetylcholine Receptor Activity
Neurotransmitter Receptor Activity
Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential
Biological Process
Protein Folding
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Intracellular Signal Transduction
Positive Regulation Of GTPase Activity
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway
Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Chemical Synaptic Transmission
Neuromuscular Synaptic Transmission
Nervous System Development
Regulation Of Locomotion
Positive Regulation Of Ion Transport
Saliva Secretion
Cognition
Regulation Of Postsynaptic Membrane Potential
Regulation Of Glial Cell Proliferation
Positive Regulation Of Intracellular Protein Transport
G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways
G alpha (i) signalling events
G alpha (i) signalling events
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Muscarinic acetylcholine receptors
G alpha (q) signalling events
Drugs
Cevimeline
Tramadol
Succinylcholine
Trospium
Oxyphenonium
Benzatropine
Ziprasidone
Disopyramide
Amitriptyline
Ipratropium
Olanzapine
Metixene
Terfenadine
Buclizine
Clozapine
Doxylamine
Trihexyphenidyl
Oxyphencyclimine
Procyclidine
Profenamine
Loxapine
Carbamoylcholine
Promazine
Hyoscyamine
Cyproheptadine
Meperidine
Imipramine
Methscopolamine bromide
Chlorpromazine
Gallamine triethiodide
Darifenacin
Tridihexethyl
Triflupromazine
Anisotropine methylbromide
Nortriptyline
Amoxapine
Amoxapine
Cinnarizine
Atropine
Nicardipine
Pirenzepine
Paroxetine
Homatropine methylbromide
Trimipramine
Scopolamine
Benzquinamide
Clidinium
Propiomazine
Propantheline
Dicyclomine
Minaprine
Tropicamide
Biperiden
Brompheniramine
Flupentixol
Cocaine
Maprotiline
Methantheline
Cycrimine
Cyclopentolate
Glycopyrronium
Bethanechol
Tolterodine
Oxybutynin
Promethazine
Pilocarpine
Doxepin
Flavoxate
Desipramine
Escitalopram
Ketamine
Quetiapine
Diphenidol
Metoclopramide
Aripiprazole
Chlorprothixene
Methotrimeprazine
Tiotropium
Solifenacin
Molindone
Staurosporine
Acetylcholine
Arecoline
Mepenzolate
NGX267
ALKS 27
ACP-104
Pizotifen
Fesoterodine
Hexocyclium
Aclidinium
Umeclidinium
Trimebutine
Dosulepin
Etoperidone
Imidafenacin
Pyrantel
Homatropine
Thonzylamine
Revefenacin
Propiverine
Rociverine
Aripiprazole lauroxil
Diseases
GWAS
Chronotype (
30696823
)
Diastolic blood pressure (
29208002
)
Ischemic stroke (cardioembolic) (
29531354
)
Longevity (90 years and older) (
25199915
)
Major depressive disorder (
27479909
)
Obesity-related traits (
23251661
)
Post bronchodilator FEV1 (
26634245
)
Western dietary pattern (
28644415
)
Urate levels (
31578528
)
Interacting Genes
16 interacting genes:
CHRM1
CHRM2
CHRM3
CHRM5
GNAI1
GNAI3
GNAO1
GNAQ
GNAZ
GNB5
MSX1
PKD1
PRKCA
SNAPIN
YWHAB
YWHAQ
5 interacting genes:
CDC14A
GNAI2
GPRASP1
GPRASP2
RGS7
Entrez ID
6000
1128
HPRD ID
03948
00338
Ensembl ID
ENSG00000182901
ENSG00000168539
Uniprot IDs
B7Z223
B7Z257
P49802
P11229
Q53XZ3
PDB IDs
2A72
2D9J
5CXV
6OIJ
6WJC
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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