PAIP1 and RND1

Data Source:
BioGRID (two hybrid)

		PAIP1	RND1
Description		poly(A) binding protein interacting protein 1	Rho family GTPase 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytosol Cytoskeleton Plasma Membrane Adherens Junction Cell Cortex Actin Cytoskeleton Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding Translation Activator Activity	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Translational Initiation Regulation Of Translational Initiation Positive Regulation Of Translation MRNA Stabilization	Actin Filament Organization Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Neuron Remodeling Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization
Pathways		Deadenylation of mRNA	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Bipolar disorder ( 21926972)
Interacting Genes		8 interacting genes: EIF3A EIF3B EIF4A1 MYB PABPC1 RND1 UBR5 WWP2	23 interacting genes: ARFIP2 ARHGAP5 CCNI COPS2 CREB3L2 EEF1A1 FRS2 FRS3 GPX8 GRB7 ID3 MYH7 MYOM3 MYZAP NEDD1 PAIP1 PDE6D PLXNA1 PLXNB1 PLXNB2 RAI14 UBXN11 ZNF212
Entrez ID		10605	27289
HPRD ID		05539	12357
Ensembl ID		ENSG00000172239	ENSG00000172602
Uniprot IDs		Q9H074	Q92730
PDB IDs		1JH4 3NTW 3RK6	2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?
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