PAIP1 and EIF3B

Data Source:
BioGRID (pull down)

		PAIP1	EIF3B
Description		poly(A) binding protein interacting protein 1	eukaryotic translation initiation factor 3 subunit B
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Synapse Extracellular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	RNA Binding Protein Binding Translation Activator Activity	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Initiation Factor Binding Molecular Adaptor Activity
	Biological Process	Translational Initiation Regulation Of Translational Initiation Positive Regulation Of Translation MRNA Stabilization	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation
Pathways		Deadenylation of mRNA	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Dimensional psychopathology (Social) ( 29496196)
Interacting Genes		8 interacting genes: EIF3A EIF3B EIF4A1 MYB PABPC1 RND1 UBR5 WWP2	18 interacting genes: BHLHB9 BRCA1 EIF3A EIF3G EIF3I EIF3J EIF4G1 IL2RB LMO2 NDUFAB1 NF2 NREP PAIP1 PBX4 RPS6KB1 TBC1D23 TNNI1 UPF1
Entrez ID		10605	8662
HPRD ID		05539	06795
Ensembl ID		ENSG00000172239	ENSG00000106263
Uniprot IDs		Q9H074	A0A024R821 A4D210 P55884
PDB IDs		1JH4 3NTW 3RK6	2KRB 2NLW 5K1H 6YBT 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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