RND1 and ARHGAP5

Data Source:
BioGRID (pull down)

		RND1	ARHGAP5
Description		Rho family GTPase 1	Rho GTPase activating protein 5
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GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Adherens Junction Cell Cortex Actin Cytoskeleton Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle	Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane
	Molecular Function	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding	GTPase Activity GTPase Activator Activity Protein Binding GTP Binding SH2 Domain Binding
	Biological Process	Actin Filament Organization Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Neuron Remodeling Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization	Cell Adhesion Rho Protein Signal Transduction Mammary Gland Development Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse	Rho GTPase cycle
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Asthma ( 29273806)
Interacting Genes		23 interacting genes: ARFIP2 ARHGAP5 CCNI COPS2 CREB3L2 EEF1A1 FRS2 FRS3 GPX8 GRB7 ID3 MYH7 MYOM3 MYZAP NEDD1 PAIP1 PDE6D PLXNA1 PLXNB1 PLXNB2 RAI14 UBXN11 ZNF212	11 interacting genes: ADRB2 ITGA5 ITGB1 PTK2B PTPN18 RASA1 RHOA RND1 RND2 RND3 SMURF2
Entrez ID		27289	394
HPRD ID		12357	04060
Ensembl ID		ENSG00000172602	ENSG00000100852
Uniprot IDs		Q92730	Q13017
PDB IDs		2CLS 2REX 3Q3J	2EE4 2EE5 5U4V
Enriched GO Terms of Interacting Partners?
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