RND1 and PLXNA1

Data Source:
HPRD (in vitro)

		RND1	PLXNA1
Description		Rho family GTPase 1	plexin A1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Adherens Junction Cell Cortex Actin Cytoskeleton Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle	Semaphorin Receptor Complex Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding	Semaphorin Receptor Activity Signaling Receptor Activity
	Biological Process	Actin Filament Organization Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Neuron Remodeling Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization	Negative Regulation Of Cell Adhesion Multicellular Organism Development Regulation Of Cell Shape Regulation Of Smooth Muscle Cell Migration Regulation Of Cell Migration Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Neuron Projection Extension
Pathways		SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse	Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling Other semaphorin interactions
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Platelet count ( 32888494) Refractive error ( 32231278) Systolic blood pressure ( 31469255) Weight ( 28552196) Whole-brain volume ( 21116278)
Interacting Genes		23 interacting genes: ARFIP2 ARHGAP5 CCNI COPS2 CREB3L2 EEF1A1 FRS2 FRS3 GPX8 GRB7 ID3 MYH7 MYOM3 MYZAP NEDD1 PAIP1 PDE6D PLXNA1 PLXNB1 PLXNB2 RAI14 UBXN11 ZNF212	9 interacting genes: AKT1 FES L1CAM NRP1 NRP2 PLXNB1 RHOD RND1 SEMA6D
Entrez ID		27289	5361
HPRD ID		12357	11868
Ensembl ID		ENSG00000172602	ENSG00000114554
Uniprot IDs		Q92730	Q9UIW2
PDB IDs		2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?
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