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MCRS1 and DVL2
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
MCRS1
DVL2
Description
microspherule protein 1
dishevelled segment polarity protein 2
Image
No pdb structure
GO Annotations
Cellular Component
Histone Acetyltransferase Complex
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Endoplasmic Reticulum
Polysome
Dendrite
Ino80 Complex
Perikaryon
NSL Complex
MLL1 Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Aggresome
Lateral Plasma Membrane
Nuclear Body
Cytoplasmic Vesicle
Apical Part Of Cell
Clathrin-coated Endocytic Vesicle
Molecular Function
G-quadruplex RNA Binding
Protein Binding
Poly(U) RNA Binding
Poly(G) Binding
Frizzled Binding
Protein Binding
Protein Kinase Binding
Protein Domain Specific Binding
Protein-macromolecule Adaptor Activity
Small GTPase Binding
Identical Protein Binding
Protein Self-association
Biological Process
DNA Repair
DNA Recombination
Cellular Protein Modification Process
Viral Process
Protein Deubiquitination
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Histone H4-K16 Acetylation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Protein Localization To Nucleolus
Neural Tube Closure
Positive Regulation Of Protein Phosphorylation
Outflow Tract Morphogenesis
Regulation Of Transcription, DNA-templated
Segment Specification
Heart Development
Convergent Extension Involved In Neural Plate Elongation
Cellular Protein Localization
Hippo Signaling
Non-canonical Wnt Signaling Pathway
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of GTPase Activity
Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-binding Transcription Factor Activity
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Membrane Organization
Positive Regulation Of Protein Tyrosine Kinase Activity
Negative Regulation Of Canonical Wnt Signaling Pathway
Cochlea Morphogenesis
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Positive Regulation Of Neuron Projection Arborization
Beta-catenin Destruction Complex Disassembly
Pathways
HATs acetylate histones
UCH proteinases
DNA Damage Recognition in GG-NER
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
Signaling by Hippo
PCP/CE pathway
PCP/CE pathway
Asymmetric localization of PCP proteins
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
WNT5A-dependent internalization of FZD4
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS
Metabolite levels (
31628463
)
Metabolite levels (small molecules and protein measures) (
27005778
)
Interacting Genes
126 interacting genes:
AGGF1
AXIN2
BACH2
BEND3
BHLHA9
BHLHE40
BLM
BRD8
BRMS1
BRMS1L
C18orf25
C2CD6
C7orf57
C8orf34
CARD9
CAVIN2
CBY2
CCDC13
CCDC136
CCDC85B
CCHCR1
CCNH
CDCA7L
CEP44
CEP70
CNTROB
COIL
CREB3L3
CSRNP1
CYSRT1
CYTIP
DAXX
DRAP1
DVL2
EGR2
ERF
EVI5
FAM9A
FNDC8
FSD2
FXR1
FXR2
GAS7
GCC1
GEM
GIGYF1
GOLGA2
GPBP1
HMBOX1
HOOK2
IKZF1
IKZF3
IKZF4
INO80E
INSYN1
JAKMIP1
KANK2
KAT7
KDM1A
KIAA1958
KRT35
KRTAP10-7
KRTAP2-3
KRTAP2-4
KXD1
LIG4
LSM6
LZTS1
MAGEA11
MAGEA6
MAPK9
MED4
MEOX1
MFAP1
MIER2
MIER3
NAA10
NAB2
NKAPD1
NOP2
OSBPL3
PBK
PBX2
PCM1
PHC2
PIBF1
PINX1
PKNOX2
PPP1R13B
PRMT5
PSTPIP1
PTEN
RABEP1
RALYL
RARA
RETREG3
RIPPLY3
SH2B2
SNAPC5
SP4
SRRM4
SSMEM1
SUV39H1
TADA2B
TBC1D1
TERT
TFAP4
TLE5
TNIP1
TNNI1
TP63
TRIM37
TRIM41
TSPYL2
UPF3B
USHBP1
WASHC3
WBP11
XIAP
ZBTB22
ZCCHC10
ZCCHC12
ZNF23
ZNF639
ZNF8
ZRANB1
103 interacting genes:
ABL1
AKAP9
AP1M1
AP2M1
ARHGEF39
ARR3
ARRB1
ARRB2
ATN1
AXIN1
BAG3
BAHD1
BCL6
BEND7
BYSL
CARD9
CCDC33
CPSF7
CSNK1E
CTBP2
DAAM1
DCUN1D1
DDI1
DPPA2
DYNLT1
EIF1B
ELOA2
ENKD1
FAM161A
FAM90A1
FZD4
GABARAP
GABARAPL1
GMCL2
GOLGA2
GRAP2
GRB2
HIP1
IHO1
KLHL12
LMO3
LRRK2
MAGOHB
MAP1LC3A
MCRS1
NOL12
NUP62CL
OTULIN
PARD6A
PCBD1
PLA2G12A
POLI
PPM1A
PPP1R16B
PRKAA1
PRKCA
PRKCB
PRKCG
PRPF3
PRPF31
PSMF1
RAC1
RBFOX1
RBPMS
RHOA
RHOXF2
RNF185
RNPS1
RUNX2
RUSC1
SCNM1
SMURF1
SNF8
SNIP1
SORBS3
SSX2IP
TAB1
TDP2
THAP1
TIFA
TLE5
TP53
TPM3
TRAF2
U2AF2
UBAC1
UBE2D3
UIMC1
USP5
USP9X
VANGL1
VHL
WAS
WT1
YES1
ZBTB48
ZBTB8A
ZGPAT
ZNF165
ZNF250
ZNF263
ZNF410
ZNF581
Entrez ID
10445
1856
HPRD ID
11298
03690
Ensembl ID
ENSG00000187778
ENSG00000004975
Uniprot IDs
A0A024R134
Q96EZ8
O14641
PDB IDs
2REY
3CBX
3CBY
3CBZ
3CC0
4WIP
5LNP
5SUY
5SUZ
6IW3
6JCK
Enriched GO Terms of Interacting Partners
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