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MCRS1 and AXIN2
Data Source:
BioGRID
(two hybrid)
MCRS1
AXIN2
Description
microspherule protein 1
axin 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Histone Acetyltransferase Complex
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Endoplasmic Reticulum
Polysome
Dendrite
Ino80 Complex
Perikaryon
NSL Complex
MLL1 Complex
Nucleus
Cytoplasm
Centrosome
Cytosol
Beta-catenin Destruction Complex
Molecular Function
G-quadruplex RNA Binding
Protein Binding
Poly(U) RNA Binding
Poly(G) Binding
Protein Binding
Beta-catenin Binding
Enzyme Binding
Ubiquitin Protein Ligase Binding
I-SMAD Binding
Biological Process
DNA Repair
DNA Recombination
Cellular Protein Modification Process
Viral Process
Protein Deubiquitination
Histone H4-K5 Acetylation
Histone H4-K8 Acetylation
Histone H4-K16 Acetylation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Protein Localization To Nucleolus
Somitogenesis
Positive Regulation Of Protein Phosphorylation
Intramembranous Ossification
Secondary Heart Field Specification
Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis
Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Cell Death
Wnt Signaling Pathway
Bone Mineralization
Regulation Of Mismatch Repair
Cellular Protein Localization
Odontogenesis
Maintenance Of DNA Repeat Elements
Negative Regulation Of Osteoblast Differentiation
MRNA Stabilization
Regulation Of Chondrocyte Development
Regulation Of Centromeric Sister Chromatid Cohesion
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Canonical Wnt Signaling Pathway
Beta-catenin-TCF Complex Assembly
Pathways
HATs acetylate histones
UCH proteinases
DNA Damage Recognition in GG-NER
TCF dependent signaling in response to WNT
Binding of TCF/LEF:CTNNB1 to target gene promoters
Degradation of AXIN
Ub-specific processing proteases
Drugs
Diseases
Tooth agenesis; Hypodontia
Oligodontia-colorectal cancer syndrome
GWAS
Blond vs. brown/black hair color (
30531825
)
Heel bone mineral density (
30598549
28869591
)
Height (
31562340
)
Refractive error (
32231278
)
Interacting Genes
126 interacting genes:
AGGF1
AXIN2
BACH2
BEND3
BHLHA9
BHLHE40
BLM
BRD8
BRMS1
BRMS1L
C18orf25
C2CD6
C7orf57
C8orf34
CARD9
CAVIN2
CBY2
CCDC13
CCDC136
CCDC85B
CCHCR1
CCNH
CDCA7L
CEP44
CEP70
CNTROB
COIL
CREB3L3
CSRNP1
CYSRT1
CYTIP
DAXX
DRAP1
DVL2
EGR2
ERF
EVI5
FAM9A
FNDC8
FSD2
FXR1
FXR2
GAS7
GCC1
GEM
GIGYF1
GOLGA2
GPBP1
HMBOX1
HOOK2
IKZF1
IKZF3
IKZF4
INO80E
INSYN1
JAKMIP1
KANK2
KAT7
KDM1A
KIAA1958
KRT35
KRTAP10-7
KRTAP2-3
KRTAP2-4
KXD1
LIG4
LSM6
LZTS1
MAGEA11
MAGEA6
MAPK9
MED4
MEOX1
MFAP1
MIER2
MIER3
NAA10
NAB2
NKAPD1
NOP2
OSBPL3
PBK
PBX2
PCM1
PHC2
PIBF1
PINX1
PKNOX2
PPP1R13B
PRMT5
PSTPIP1
PTEN
RABEP1
RALYL
RARA
RETREG3
RIPPLY3
SH2B2
SNAPC5
SP4
SRRM4
SSMEM1
SUV39H1
TADA2B
TBC1D1
TERT
TFAP4
TLE5
TNIP1
TNNI1
TP63
TRIM37
TRIM41
TSPYL2
UPF3B
USHBP1
WASHC3
WBP11
XIAP
ZBTB22
ZCCHC10
ZCCHC12
ZNF23
ZNF639
ZNF8
ZRANB1
52 interacting genes:
AMOT
ANKRD6
AP1M1
APC
APC2
BARD1
BTRC
BYSL
C2orf68
CAPN7
CCDC112
CHIC2
CSNK1E
CTAG2
CTNNB1
CWF19L2
ELOA
FAM161A
FBP1
FBP2
GSK3B
HEMGN
HOXB5
KCNK12
KIFC3
KRTAP10-10
KRTAP10-8
KRTAP4-5
KRTAP9-2
LNX1
MCRS1
PPP2R5A
PRDX1
PSMB2
RANGAP1
SCNM1
SMAD1
SMAD3
SMAD7
STX11
TCEA2
TCEANC
TGFB1
TOP3B
TSGA10
TXLNA
TXLNB
ZNF124
ZNF189
ZNF417
ZNF587
ZNF648
Entrez ID
10445
8313
HPRD ID
11298
04935
Ensembl ID
ENSG00000187778
ENSG00000168646
Uniprot IDs
A0A024R134
Q96EZ8
E7ES00
Q9Y2T1
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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