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PGRMC2 and BAG4
Data Source:
BioGRID
(two hybrid)
PGRMC2
BAG4
Description
progesterone receptor membrane component 2
BAG cochaperone 4
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Envelope
Endoplasmic Reticulum
Endomembrane System
Membrane
Integral Component Of Membrane
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Molecular Function
Steroid Hormone Receptor Activity
Steroid Binding
Protein Binding
Heme Transmembrane Transporter Activity
Heme Binding
Adenyl-nucleotide Exchange Factor Activity
RNA Binding
Protein Binding
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Protein-containing Complex Binding
Chaperone Binding
Biological Process
Heme Transport
Steroid Hormone Mediated Signaling Pathway
Adipose Tissue Development
Protein Folding
Positive Regulation Of Fibroblast Migration
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Peptidyl-serine Phosphorylation
Tumor Necrosis Factor-mediated Signaling Pathway
Negative Regulation Of Apoptotic Process
Positive Regulation Of Cell Adhesion
Protein Stabilization
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Protein Kinase B Signaling
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Protein Localization To Plasma Membrane
Negative Regulation Of MRNA Modification
Ruffle Assembly
Regulation Of Cellular Response To Heat
Negative Regulation Of Protein Targeting To Mitochondrion
Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Pathways
Regulation of HSF1-mediated heat shock response
Signaling by FGFR1 in disease
TNF signaling
Signaling by plasma membrane FGFR1 fusions
Drugs
Diseases
GWAS
Bone mineral density (total hip) (
29883787
)
Autism spectrum disorder or schizophrenia (
28540026
)
Schizophrenia (
28991256
29483656
)
Interacting Genes
57 interacting genes:
AQP10
ART5
BAG4
C5
COX20
CYB561D2
CYP4F2
DGAT2L6
DHRSX
EI24
FA2H
FAXDC2
FXYD6
FXYD6-FXYD2
GET3
GHITM
GPR151
ITGAM
ITPRIP
LPAR3
MALL
MFHAS1
MFSD5
ORMDL1
PEDS1-UBE2V1
PEX16
PGRMC1
PLLP
PMP22
RNF8
RUSF1
SFXN1
SLC16A13
SLC30A8
SLC38A1
SLC39A13
SLC9B2
SMPD2
ST6GAL2
STX3
TAS2R19
TECR
TF
TMEM107
TMEM187
TMEM19
TMEM208
TMEM60
TMEM86A
TMEM86B
TSPAN2
UBXN8
VAPA
VEZT
YIPF2
ZDHHC21
ZFPL1
117 interacting genes:
ABI2
ACOT7
ADAMTSL4
ALG13
APOBEC1
ARID5A
ATAD2
ATP23
BAP1
BCAS3
BCL2
BCL6B
BEX1
BLZF1
C3orf38
CASP2
CASZ1
CBFA2T2
CCL5
DDIT4L
DIRAS3
DZIP3
EFEMP1
EPSTI1
ERRFI1
FAM214B
FAM222B
FARS2
FTH1
FYN
GLCE
GPANK1
GPS2
GRAP2
HOXA1
HSPA1A
HSPA1B
HSPA1L
HSPA2
HSPA6
HSPA8
IL13RA2
IL24
IST1
ITIH5
KCTD6
KCTD7
KIF5B
KLK5
KLK7
KLK9
KRTAP13-1
KRTAP13-4
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP6-3
LASP1
LRATD2
LYPD3
MAGED1
MEI4
MRC2
MTA3
MYOZ1
MYOZ3
MYPOP
NAT2
ODF1
ODF3L1
P4HA3
PDCD6
PDLIM2
PEF1
PGRMC2
PHF19
PLAC8
PPIL6
PPP1R32
PRDM14
PSMB5
PYCR3
RAMAC
RASL10B
RHOBTB2
RNF20
RPL22
RUNX1
SAMD4A
SAXO1
SCGB3A1
SH3RF2
SIAH1
SNRPB
SNRPC
SS18L1
SUOX
TBC1D3B
TBC1D3G
TBC1D7
TCL1B
TEKT5
TFAP2D
THRSP
TINAGL1
TLE5
TNFRSF1A
TNFRSF25
TRAPPC6A
TSG101
UNKL
USP22
VPS37C
ZBTB45
ZBTB5
ZIM2
Entrez ID
10424
9530
HPRD ID
09665
04861
Ensembl ID
ENSG00000164040
ENSG00000156735
Uniprot IDs
O15173
O95429
PDB IDs
1M62
1M7K
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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