PGRMC2 and ITPRIP

Data Source:
BioGRID (two hybrid)

		PGRMC2	ITPRIP
Description		progesterone receptor membrane component 2	inositol 1,4,5-trisphosphate receptor interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endomembrane System Membrane Integral Component Of Membrane	Nuclear Outer Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Steroid Hormone Receptor Activity Steroid Binding Protein Binding Heme Transmembrane Transporter Activity Heme Binding	Protein Kinase Inhibitor Activity Protein Binding
	Biological Process	Heme Transport Steroid Hormone Mediated Signaling Pathway Adipose Tissue Development	Negative Regulation Of Protein Kinase Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Drugs
Diseases
GWAS		Bone mineral density (total hip) ( 29883787)	Mean platelet volume ( 32888494)
Interacting Genes		57 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LPAR3 MALL MFHAS1 MFSD5 ORMDL1 PEDS1-UBE2V1 PEX16 PGRMC1 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VAPA VEZT YIPF2 ZDHHC21 ZFPL1	5 interacting genes: ITPR1 NLGN3 PGRMC2 RASSF3 SGTB
Entrez ID		10424	85450
HPRD ID		09665	13892
Ensembl ID		ENSG00000164040	ENSG00000148841
Uniprot IDs		O15173	Q8IWB1
PDB IDs
Enriched GO Terms of Interacting Partners?
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