CD2BP2 and TRAPPC6A

Data Source:
BioGRID (two hybrid)

		CD2BP2	TRAPPC6A
Description		CD2 cytoplasmic tail binding protein 2	trafficking protein particle complex subunit 6A
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GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm U5 SnRNP Cytoplasm Cytosol Nuclear Speck U4/U6 X U5 Tri-snRNP Complex	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding	Protein Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome Negative Regulation Of Phosphatase Activity	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly
Pathways		mRNA Splicing - Major Pathway	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs			S-palmitoyl-L-cysteine
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		14 interacting genes: ACAD11 AKNA CD2 CHRM3 CSNK2A1 LRRK1 PRPF6 PSMF1 SMU1 SNRPB TRAPPC6A TXNL4A WBP11 ZNHIT2	47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2
Entrez ID		10421	79090
HPRD ID		05127	14503
Ensembl ID		ENSG00000169217	ENSG00000007255
Uniprot IDs		A0A024QZC1 O95400	B7TZ90 O75865
PDB IDs		1GYF 1L2Z 1SYX 4BWS	2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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