CD2BP2 and LRRK1

Data Source:
BioGRID (pull down)

		CD2BP2	LRRK1
Description		CD2 cytoplasmic tail binding protein 2	leucine rich repeat kinase 1
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm U5 SnRNP Cytoplasm Cytosol Nuclear Speck U4/U6 X U5 Tri-snRNP Complex	Cytoplasm Mitochondrion Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding	Protein Serine/threonine Phosphatase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome Negative Regulation Of Phosphatase Activity	Protein Phosphorylation Protein Dephosphorylation Signal Transduction Osteoclast Development Bone Resorption Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Intracellular Signal Transduction
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Central corneal thickness ( 32528159 28171582 31798171 29760442) Corneal structure ( 23291589) Height ( 28552196)
Interacting Genes		14 interacting genes: ACAD11 AKNA CD2 CHRM3 CSNK2A1 LRRK1 PRPF6 PSMF1 SMU1 SNRPB TRAPPC6A TXNL4A WBP11 ZNHIT2	51 interacting genes: ABL1 BAG1 BAG2 BAG3 BAG5 BLOC1S5 C11orf52 CBLB CCL21 CD2BP2 CDC42EP3 CHGB CKAP2 CLVS1 CPLX3 CWC15 ECHS1 EGFR ENKUR EPHA8 FAM184A FBXL14 FGFR2 FLT4 FOXP1 GAK GNAZ GPBP1L1 ITCH KIF20A MATK MTG1 NEK1 NUDT16L1 ODF2 PAK6 PDCD4 PLK1 POLR2M RAB29 RET SCEL SH2D2A SNX21 SNX9 STUB1 TCF25 TEC TEX33 TIRAP VGLL4
Entrez ID		10421	79705
HPRD ID		05127	14319
Ensembl ID		ENSG00000169217	ENSG00000154237
Uniprot IDs		A0A024QZC1 O95400	Q38SD2
PDB IDs		1GYF 1L2Z 1SYX 4BWS
Enriched GO Terms of Interacting Partners?
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