SUMO3 and ZBTB33

Data Source:
BioGRID (two hybrid)

		SUMO3	ZBTB33
Description		small ubiquitin like modifier 3	zinc finger and BTB domain containing 33
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GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytoplasm PML Body	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane
	Molecular Function	Protein Binding Protein Tag Ubiquitin-like Protein Ligase Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Methyl-CpG Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Sumoylation Negative Regulation Of DNA Binding Regulation Of Protein Localization To Nucleus	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway Intracellular Signal Transduction Negative Regulation Of Transcription, DNA-templated
Pathways		SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) SUMO is proteolytically processed SUMOylation of DNA damage response and repair proteins SUMOylation of transcription factors SUMOylation of transcription cofactors SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins SUMOylation of DNA replication proteins SUMOylation of immune response proteins Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS		Delirium ( 29631748)
Interacting Genes		53 interacting genes: ANXA7 BLM CCNE2 CDKN1A CEBPA CHAF1A CUL3 DAXX EGLN3 FAM221A FOS HIPK2 HOMEZ HSF1 HSF2 JUN KALRN MAPKAPK3 PFDN1 PIAS1 PIAS2 PIAS3 PIAS4 PML RANGAP1 RNF111 RNF8 SAE1 SENP1 SENP2 SENP5 SMN1 SOX10 SOX6 SP100 TDG TDP2 TK1 TP53BP2 TTR UBA2 UBE2I UBE3A UPF2 USP25 USPL1 VIM WWTR1 YAP1 ZBTB33 ZBTB39 ZCCHC12 ZNF496	9 interacting genes: CBFA2T3 CTNND1 GSDMD GYS1 NCOR1 NUDT22 SUMO2 SUMO3 TRIML2
Entrez ID		6612	10009
HPRD ID		03754	02269
Ensembl ID		ENSG00000184900	ENSG00000177485
Uniprot IDs		P55854	Q86T24
PDB IDs		1U4A 2IO1 2MP2 6K5R 6NNQ	2LT7 3FKC 3M4T 3M8V 4F6M 4F6N 5VMU 5VMV 5VMW 5VMX 5VMY 5VMZ 6DF5 6DF8 6DF9 6DFA 6DFB 6DFC 6V8U
Enriched GO Terms of Interacting Partners?
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