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SUMO3 and ZCCHC12
Data Source:
BioGRID
(two hybrid)
SUMO3
ZCCHC12
Description
small ubiquitin like modifier 3
zinc finger CCHC-type containing 12
Image
No pdb structure
GO Annotations
Cellular Component
Kinetochore
Nucleus
Nucleoplasm
Cytoplasm
PML Body
Nucleus
Molecular Function
Protein Binding
Protein Tag
Ubiquitin-like Protein Ligase Binding
Nucleic Acid Binding
Protein Binding
Zinc Ion Binding
Biological Process
Protein Sumoylation
Negative Regulation Of DNA Binding
Regulation Of Protein Localization To Nucleus
Pathways
SUMO is conjugated to E1 (UBA2:SAE1)
SUMO is transferred from E1 to E2 (UBE2I, UBC9)
SUMO is proteolytically processed
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of transcription cofactors
SUMOylation of intracellular receptors
SUMOylation of intracellular receptors
SUMOylation of chromatin organization proteins
SUMOylation of DNA replication proteins
SUMOylation of immune response proteins
Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS
Delirium (
29631748
)
Interacting Genes
53 interacting genes:
ANXA7
BLM
CCNE2
CDKN1A
CEBPA
CHAF1A
CUL3
DAXX
EGLN3
FAM221A
FOS
HIPK2
HOMEZ
HSF1
HSF2
JUN
KALRN
MAPKAPK3
PFDN1
PIAS1
PIAS2
PIAS3
PIAS4
PML
RANGAP1
RNF111
RNF8
SAE1
SENP1
SENP2
SENP5
SMN1
SOX10
SOX6
SP100
TDG
TDP2
TK1
TP53BP2
TTR
UBA2
UBE2I
UBE3A
UPF2
USP25
USPL1
VIM
WWTR1
YAP1
ZBTB33
ZBTB39
ZCCHC12
ZNF496
26 interacting genes:
ABHD5
APP
APPBP2
ATP6V0C
CD207
FADD
FATE1
KPNA3
LMO1
MAGEA11
MCRS1
MX1
PNMA1
RNF40
RUSF1
SPOP
STX2
SUMO1
SUMO2
SUMO3
TADA2A
TFCP2
TMEM43
TMEM79
TNF
UBE2I
Entrez ID
6612
170261
HPRD ID
03754
06616
Ensembl ID
ENSG00000184900
ENSG00000174460
Uniprot IDs
P55854
Q6PEW1
PDB IDs
1U4A
2IO1
2MP2
6K5R
6NNQ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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