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SUMO3

Description small ubiquitin like modifier 3
Image
GO Annotations Cellular Component
  • Kinetochore
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • PML Body
Molecular Function
  • Protein Binding
  • Protein Tag
  • Ubiquitin-like Protein Ligase Binding
Biological Process
  • Protein Sumoylation
  • Negative Regulation Of DNA Binding
  • Regulation Of Protein Localization To Nucleus
Pathways
  • SUMO is conjugated to E1 (UBA2:SAE1)
  • SUMO is transferred from E1 to E2 (UBE2I, UBC9)
  • SUMO is proteolytically processed
  • SUMOylation of DNA damage response and repair proteins
  • SUMOylation of transcription factors
  • SUMOylation of transcription cofactors
  • SUMOylation of intracellular receptors
  • SUMOylation of intracellular receptors
  • SUMOylation of chromatin organization proteins
  • SUMOylation of DNA replication proteins
  • SUMOylation of immune response proteins
  • Formation of Incision Complex in GG-NER
Drugs
Diseases
GWAS
  • Delirium ( 29631748)
Novel Interacting Genes 2 novel interacting genes: MORC3 TRAPPC10
Interacting Genes 53 interacting genes: ANXA7 BLM CCNE2 CDKN1A CEBPA CHAF1A CUL3 DAXX EGLN3 FAM221A FOS HIPK2 HOMEZ HSF1 HSF2 JUN KALRN MAPKAPK3 PFDN1 PIAS1 PIAS2 PIAS3 PIAS4 PML RANGAP1 RNF111 RNF8 SAE1 SENP1 SENP2 SENP5 SMN1 SOX10 SOX6 SP100 TDG TDP2 TK1 TP53BP2 TTR UBA2 UBE2I UBE3A UPF2 USP25 USPL1 VIM WWTR1 YAP1 ZBTB33 ZBTB39 ZCCHC12 ZNF496
Entrez ID 6612
HPRD ID 03754
Ensembl ID ENSG00000184900
Uniprot IDs P55854
PDB IDs 1U4A 2IO1 2MP2 6K5R 6NNQ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025