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SRA1 and ATF2
Data Source:
BioGRID
(far western blotting)
SRA1
ATF2
Description
steroid receptor RNA activator 1
activating transcription factor 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Cytosol
Plasma Membrane
Microtubule Cytoskeleton
SCAR Complex
Cell Leading Edge
Intercellular Bridge
Ribonucleoprotein Complex
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrial Outer Membrane
Site Of Double-strand Break
H4 Histone Acetyltransferase Complex
Molecular Function
Steroid Receptor RNA Activator RNA Binding
DNA Binding
Transcription Coactivator Activity
Protein Binding
Nuclear Receptor Coactivator Activity
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Activating Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
DNA-binding Transcription Factor Activity
Histone Acetyltransferase Activity
Protein Binding
CAMP Response Element Binding Protein Binding
H4 Histone Acetyltransferase Activity
Protein Kinase Binding
CAMP Response Element Binding
H2B Histone Acetyltransferase Activity
Protein-containing Complex Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Regulation Of Mitotic Cell Cycle
Cell Differentiation
Regulation Of Apoptotic Process
Negative Regulation Of Myoblast Differentiation
Positive Regulation Of Transcription, DNA-templated
Cellular Response To Estrogen Stimulus
Negative Regulation Of Transcription By RNA Polymerase II
Outflow Tract Morphogenesis
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Response To Osmotic Stress
Cellular Response To DNA Damage Stimulus
Response To Water Deprivation
Positive Regulation Of Gene Expression
Negative Regulation Of Angiogenesis
Intra-S DNA Damage Checkpoint
Positive Regulation Of Transforming Growth Factor Beta2 Production
Positive Regulation Of Neuron Apoptotic Process
Histone H4 Acetylation
Histone H2B Acetylation
Fat Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Epithelial Cell Proliferation
Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of DNA-binding Transcription Factor Activity
Adipose Tissue Development
Amelogenesis
Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Pathways
Transcriptional activation of mitochondrial biogenesis
HATs acetylate histones
Circadian Clock
Activation of the AP-1 family of transcription factors
TP53 Regulates Transcription of DNA Repair Genes
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Estrogen-dependent gene expression
NGF-stimulated transcription
NGF-stimulated transcription
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK4 (GCN2) to amino acid deficiency
Drugs
Pseudoephedrine
Diseases
GWAS
Refractive error (
32231278
)
Schizophrenia (
28991256
)
Serum immune biomarker levels (
32066700
)
Intake of total sugars (
31005972
)
Metabolite levels (
23823483
)
Interacting Genes
30 interacting genes:
ALX1
ATF1
ATF2
ATF3
ATF4
BLZF1
BTG2
CEBPA
CREB1
DDIT3
DMTF1
E2F3
EGR1
EGR2
ESR1
ESR2
ESRRG
ETS1
ETS2
FOS
FOSB
FOSL2
GATA1
GTF2B
GTF2H2
GTF3C5
HAND1
NR3C1
TFAP2A
UBE2Z
63 interacting genes:
APP
AR
ATF3
ATF4
ATF7
BACH1
BANP
BATF
CCDC6
CCND1
CEBPA
CEBPB
CEBPG
CENPQ
CREB5
CSNK2A1
CSNK2A2
DDIT3
DNMT3L
EDF1
ETS1
EXOSC8
FOS
FOSB
FOSL1
FOSL2
GTF2F2
H2BC21
HMGA1
IRF2BP1
JDP2
JUN
KIFC3
LHX8
MACROH2A1
MAPK1
MAPK10
MAPK11
MAPK13
MAPK14
MAPK8
MAPK9
MAPKAPK5
MLH1
NBN
NCOA6
PIAS2
PML
PRKCE
RB1
RNF4
RPS6KA5
RUVBL2
SMAD3
SMAD4
SPOPL
SRA1
SUMO1
THRB
UBE2I
UTF1
XPO1
YY1
Entrez ID
10011
1386
HPRD ID
18716
00443
Ensembl ID
ENSG00000213523
ENSG00000115966
Uniprot IDs
Q9HD15
A4D7V5
P15336
PDB IDs
2MGX
4NBO
1BHI
1T2K
4H36
Enriched GO Terms of Interacting Partners
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