SRA1 and FOSB

Data Source:
BioGRID (far western blotting)

		SRA1	FOSB
Description		steroid receptor RNA activator 1	FosB proto-oncogene, AP-1 transcription factor subunit
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Plasma Membrane Microtubule Cytoskeleton SCAR Complex Cell Leading Edge Intercellular Bridge Ribonucleoprotein Complex	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Steroid Receptor RNA Activator RNA Binding DNA Binding Transcription Coactivator Activity Protein Binding Nuclear Receptor Coactivator Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Regulation Of Mitotic Cell Cycle Cell Differentiation Regulation Of Apoptotic Process Negative Regulation Of Myoblast Differentiation Positive Regulation Of Transcription, DNA-templated Cellular Response To Estrogen Stimulus	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Female Pregnancy Response To Mechanical Stimulus Response To Progesterone Cellular Response To Hormone Stimulus Response To Drug Response To Morphine Positive Regulation Of Transcription By RNA Polymerase II Response To Corticosterone Response To CAMP Cellular Response To Calcium Ion
Pathways			Estrogen-dependent gene expression NGF-stimulated transcription NGF-stimulated transcription
Drugs
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 28991256) Serum immune biomarker levels ( 32066700)	Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Heel bone mineral density ( 30598549 28869591)
Interacting Genes		30 interacting genes: ALX1 ATF1 ATF2 ATF3 ATF4 BLZF1 BTG2 CEBPA CREB1 DDIT3 DMTF1 E2F3 EGR1 EGR2 ESR1 ESR2 ESRRG ETS1 ETS2 FOS FOSB FOSL2 GATA1 GTF2B GTF2H2 GTF3C5 HAND1 NR3C1 TFAP2A UBE2Z	28 interacting genes: AGXT ATF2 CENPO CREB5 CYTH4 DNMT3L ENKD1 EP300 FAM222B FAM90A1 FOXP3 GLIS2 JUN JUNB JUND NCK2 NEDD9 PHC2 PHF1 POGZ POU6F2 ROR2 SRA1 TENT5B TLE5 TLX3 VEZF1 ZC3H10
Entrez ID		10011	2354
HPRD ID		18716	01270
Ensembl ID		ENSG00000213523	ENSG00000125740
Uniprot IDs		Q9HD15	A0A024R0P6 K7EKC1 P53539
PDB IDs		2MGX 4NBO	5VPA 5VPB 5VPC 5VPD 5VPE 5VPF 6UCI 6UCL 6UCM
Enriched GO Terms of Interacting Partners?
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