ACTN3 and TRIM29

Data Source:
BioGRID (two hybrid)

		ACTN3	TRIM29
Description		actinin alpha 3	tripartite motif containing 29
Image
GO Annotations	Cellular Component	Cytosol Actin Filament Focal Adhesion Pseudopodium Extracellular Exosome	Lysosome Adherens Junction
	Molecular Function	Actin Binding Integrin Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Identical Protein Binding Ion Channel Binding	P53 Binding Protein Binding Zinc Ion Binding Identical Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Regulation Of The Force Of Skeletal Muscle Contraction Skeletal Muscle Atrophy Transition Between Fast And Slow Fiber Response To Denervation Involved In Regulation Of Muscle Adaptation Muscle Filament Sliding Regulation Of Apoptotic Process Negative Regulation Of Glycolytic Process Focal Adhesion Assembly Positive Regulation Of Skeletal Muscle Tissue Growth Negative Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Oxidative Phosphorylation Negative Regulation Of Cold-induced Thermogenesis Regulation Of Aerobic Respiration Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate	Negative Regulation Of Transcription By RNA Polymerase II Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus
Pathways		Nephrin family interactions Striated Muscle Contraction	Interferon gamma signaling
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) Frontotemporal dementia with GRN mutation ( 29724592)	Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Retinal detachment or retinal break ( 31816047) Stroke (pediatric) ( 22990015)
Interacting Genes		61 interacting genes: ABI3 ACTN1 ACTN2 ACTN4 ADORA2A ASB9 ATP23 BRCA1 C1orf94 C20orf85 C2CD6 CADPS CTAG1A CTAG1B CTDSP1 CXCL5 DDAH2 DUX1 DUX4L9 ECM1 FAM90A1 GLIS2 HGS HOXD12 HSF2BP IVD KCTD6 KRT6C LHX3 LINC01554 LNX1 MAGEA6 MICALL2 MYOT MYOZ1 MYPN NDUFAB1 NEBL NKAPD1 NRAP ODF3B PCCB PKP2 PLEKHG2 POU6F2 PPP1R18 PTK6 REL RNF111 RTP5 SNAI1 SOHLH1 SUMO1P1 SYNPO2L TRAF1 TRAF2 TRIM29 TTN USP2 ZNF343 ZNF426	54 interacting genes: ACTN3 ANKS1A ATM CARD9 CCDC57 CDC34 CEP70 CRACR2A DISC1 DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 IKBKG JAKMIP2 KAT5 KRT35 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MTUS2 MYO15B NFKBID POLR2D POLR2E PRICKLE3 PRKCA RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM
Entrez ID		89	23650
HPRD ID		02148	10280
Ensembl ID		ENSG00000248746	ENSG00000137699
Uniprot IDs		A0A087WSZ2 B4DZQ2 Q08043	A0A024R3J1 B7Z5V5 B7Z8U9 E9PRL4 Q14134
PDB IDs		1TJT 1WKU 3LUE	2CSV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?