TRIM29 and TRIM11

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRIM29	TRIM11
Description		tripartite motif containing 29	tripartite motif containing 11
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Adherens Junction	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	P53 Binding Protein Binding Zinc Ion Binding Identical Protein Binding Cadherin Binding Involved In Cell-cell Adhesion	Protein Binding Transcription Factor Binding Zinc Ion Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus	Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Viral Transcription Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of Neurogenesis Defense Response To Virus Negative Regulation Of Viral Release From Host Cell
Pathways		Interferon gamma signaling	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Retinal detachment or retinal break ( 31816047) Stroke (pediatric) ( 22990015)	Hip circumference (psychosocial stress interaction) ( 25271088) Non-Richardson's syndrome vs Richardson's syndrome in progressive supranuclear palsy ( 30066433)
Interacting Genes		54 interacting genes: ACTN3 ANKS1A ATM CARD9 CCDC57 CDC34 CEP70 CRACR2A DISC1 DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 IKBKG JAKMIP2 KAT5 KRT35 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MTUS2 MYO15B NFKBID POLR2D POLR2E PRICKLE3 PRKCA RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM	7 interacting genes: MED15 PAX6 RNF126 TRIM27 TRIM29 TRIM35 USP14
Entrez ID		23650	81559
HPRD ID		10280	07429
Ensembl ID		ENSG00000137699	ENSG00000154370
Uniprot IDs		A0A024R3J1 B7Z5V5 B7Z8U9 E9PRL4 Q14134	Q96F44
PDB IDs		2CSV
Enriched GO Terms of Interacting Partners?
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