TRIM29 and MYO15B

Data Source:
BioGRID (two hybrid)

		TRIM29	MYO15B
Description		tripartite motif containing 29	myosin XVB
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GO Annotations	Cellular Component	Lysosome Adherens Junction
	Molecular Function	P53 Binding Protein Binding Zinc Ion Binding Identical Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Retinal detachment or retinal break ( 31816047) Stroke (pediatric) ( 22990015)
Interacting Genes		54 interacting genes: ACTN3 ANKS1A ATM CARD9 CCDC57 CDC34 CEP70 CRACR2A DISC1 DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 IKBKG JAKMIP2 KAT5 KRT35 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MTUS2 MYO15B NFKBID POLR2D POLR2E PRICKLE3 PRKCA RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM	95 interacting genes: ABI2 ADAMTSL4 BEND7 BHLHB9 C11orf1 C7orf57 CARD9 CCNC CEP57L1 COIL CRX DNAJA3 DUSP21 ERAS FAM9B FHL2 GAB2 GADD45GIP1 GFAP GINS3 HOXA1 IHO1 IKZF3 KATNBL1 KCNJ6 KIAA0408 KIF24 KIFC3 KLF4 KLHL12 KRT13 KRT34 KRT35 KRT75 LIMS1 MTUS2 MYOZ3 NADSYN1 NBPF19 NDUFA12 NECAB2 NEDD4 NEFL NHSL2 NKAPD1 NOTCH2NLA NR1D2 NUP62 PAK5 PKNOX2 PLEKHA3 PNMA1 PNMA5 POU6F2 PPM1K PPP1R32 PRKAR1B RAD54B RBM11 RCN1 RCN3 REL RPH3AL RUNDC3A SLA SORBS3 SPATC1L SPRED2 SSBP4 TCF12 TCF4 TEX13A TFIP11 TLE5 TPRN TRAF2 TRIM14 TRIM27 TRIM29 TRIM54 TSC22D4 UBQLN2 VGLL3 ZBED1 ZBTB10 ZBTB3 ZBTB32 ZBTB8A ZCCHC14 ZMAT1 ZNF114 ZNF438 ZNF774 ZNF837 ZNRD2
Entrez ID		23650	80022
HPRD ID		10280
Ensembl ID		ENSG00000137699	ENSG00000266714
Uniprot IDs		A0A024R3J1 B7Z5V5 B7Z8U9 E9PRL4 Q14134	Q96JP2 Q9H614
PDB IDs		2CSV	2DLP
Enriched GO Terms of Interacting Partners?
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