TRIM29 and SHOX2

Data Source:
BioGRID (two hybrid)

		TRIM29	SHOX2
Description		tripartite motif containing 29	short stature homeobox 2
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Adherens Junction	Chromatin Nucleus
	Molecular Function	P53 Binding Protein Binding Zinc Ion Binding Identical Protein Binding Cadherin Binding Involved In Cell-cell Adhesion	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Innate Immune Response Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Osteoblast Differentiation Positive Regulation Of Mesenchymal Cell Proliferation Chondrocyte Development Heart Valve Development Cardiac Atrium Morphogenesis Regulation Of Transcription By RNA Polymerase II Nervous System Development Heart Development Regulation Of Chondrocyte Differentiation Embryonic Forelimb Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Embryonic Digestive Tract Morphogenesis Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Axonogenesis Embryonic Skeletal Joint Morphogenesis Cartilage Development Involved In Endochondral Bone Morphogenesis Muscle Tissue Morphogenesis Sinoatrial Node Cell Development Regulation Of Branching Morphogenesis Of A Nerve
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Corneal curvature ( 22969067) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Resistance to antihypertensive treatment in hypertension ( 31545351) Retinal detachment or retinal break ( 31816047) Stroke (pediatric) ( 22990015)	Body mass index ( 26426971) Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 25429064 23563607 31562340) Idiopathic dilated cardiomyopathy ( 29495422) Lung cancer in never smokers ( 28604730) Monobrow ( 27182965) Neurociticism ( 29500382) Neuroticism ( 29255261) Pulse pressure ( 30224653)
Interacting Genes		54 interacting genes: ACTN3 ANKS1A ATM CARD9 CCDC57 CDC34 CEP70 CRACR2A DISC1 DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 H4C1 HCLS1 HDAC9 HINT1 IKBKG JAKMIP2 KAT5 KRT35 LZTS2 MAD1L1 MAPKAPK2 MED7 MID2 MLH1 MSH2 MTUS2 MYO15B NFKBID POLR2D POLR2E PRICKLE3 PRKCA RNF8 SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2C UBE2E1 UBE2I VIM	3 interacting genes: CDK4 TRIM29 ZDHHC17
Entrez ID		23650	6474
HPRD ID		10280	03936
Ensembl ID		ENSG00000137699	ENSG00000168779
Uniprot IDs		A0A024R3J1 B7Z5V5 B7Z8U9 E9PRL4 Q14134	A6NLG4 O60902
PDB IDs		2CSV
Enriched GO Terms of Interacting Partners?
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