PKP4 and OSGEP

Data Source:
BioGRID (two hybrid)

		PKP4	OSGEP
Description		plakophilin 4	O-sialoglycoprotein endopeptidase
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cornified Envelope Nucleus Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Adherens Junction Cytoplasmic Side Of Plasma Membrane Cell Junction Desmosome Midbody Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Spindle Midzone Mitotic Spindle	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Plasma Membrane Nuclear Speck
	Molecular Function	Protein Binding Cadherin Binding	Protein Binding Metal Ion Binding N(6)-L-threonylcarbamoyladenine Synthase Activity
	Biological Process	Cell-cell Junction Assembly Cell-cell Signaling Regulation Of Cell Adhesion Keratinization Positive Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Cornification Cell-cell Adhesion	TRNA Threonylcarbamoyladenosine Modification
Pathways		Keratinization Formation of the cornified envelope	tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Borderline personality disorder ( 28632202) Obesity-related traits ( 23251661) Restless legs syndrome ( 29029846)	Food addiction ( 27106561)
Interacting Genes		19 interacting genes: ATPAF2 CDH1 CDH2 CDH5 DSC3 DSP ERBIN GABARAP GOLGA2 LNX1 LZTS2 MINK1 OSGEP PAXIP1 PDZD2 PGAM1 PSEN1 TRIM23 UBASH3B	25 interacting genes: CIAPIN1 CRIP2 EMCN GP1BA HPS6 LAGE3 LENG1 MUC1 NR3C1 NVL OPTC PDE4DIP PKP4 RBM48 REX1BD SF3B3 SHC1 SP110 SPRED1 TNS1 TP53RK WDR82 WIZ ZNF579 ZNF775
Entrez ID		8502	55644
HPRD ID		05043	10133
Ensembl ID		ENSG00000144283	ENSG00000092094
Uniprot IDs		Q99569	Q9NPF4
PDB IDs			6GWJ
Enriched GO Terms of Interacting Partners?
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