OSGEP and GP1BA

Data Source:
HPRD (in vitro)

		OSGEP	GP1BA
Description		O-sialoglycoprotein endopeptidase	glycoprotein Ib platelet subunit alpha
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GO Annotations	Cellular Component	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Plasma Membrane Nuclear Speck	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Extracellular Matrix Anchored Component Of External Side Of Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding N(6)-L-threonylcarbamoyladenine Synthase Activity	Protein Binding Thrombin-activated Receptor Activity
	Biological Process	TRNA Threonylcarbamoyladenosine Modification	Cell Morphogenesis Cell Adhesion Cell Surface Receptor Signaling Pathway Blood Coagulation Blood Coagulation, Intrinsic Pathway Platelet Activation Regulation Of Blood Coagulation Fibrinolysis Regulation Of Megakaryocyte Differentiation Thrombin-activated Receptor Signaling Pathway Platelet Aggregation
Pathways		tRNA modification in the nucleus and cytosol	Intrinsic Pathway of Fibrin Clot Formation GP1b-IX-V activation signalling Platelet Adhesion to exposed collagen Platelet Aggregation (Plug Formation) RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Defective F9 activation
Drugs			Ibuprofen Egaptivon pegol liposomal prostaglandin E1 Dexibuprofen
Diseases			Bernard-Soulier syndrome; Giant platelet syndrome
GWAS		Food addiction ( 27106561)	Blood protein levels ( 30072576 29875488) Mean platelet volume ( 32888494 27863252) Platelet count ( 22139419 29403010 32888494 20139978 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494)
Interacting Genes		25 interacting genes: CIAPIN1 CRIP2 EMCN GP1BA HPS6 LAGE3 LENG1 MUC1 NR3C1 NVL OPTC PDE4DIP PKP4 RBM48 REX1BD SF3B3 SHC1 SP110 SPRED1 TNS1 TP53RK WDR82 WIZ ZNF579 ZNF775	17 interacting genes: CTSG DDIT3 F11 F12 F2 FLNA FLNB GP5 GP9 ITGAM KNG1 OSGEP PIK3R1 SELP TPST1 VWF YWHAZ
Entrez ID		55644	2811
HPRD ID		10133	01976
Ensembl ID		ENSG00000092094	ENSG00000185245
Uniprot IDs		Q9NPF4	L7UYB8 P07359
PDB IDs		6GWJ	1GWB 1K13 1M0Z 1M10 1OOK 1P8V 1P9A 1QYY 1SQ0 1U0N 2BP3 3P72 3PMH 4C2A 4C2B 4CH2 4CH8 4MGX 4YR6
Enriched GO Terms of Interacting Partners?
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