OSGEP and SP110

Data Source:
BioGRID (two hybrid)

		OSGEP	SP110
Description		O-sialoglycoprotein endopeptidase	SP110 nuclear body protein
Image			No pdb structure
GO Annotations	Cellular Component	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Plasma Membrane Nuclear Speck	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Metal Ion Binding N(6)-L-threonylcarbamoyladenine Synthase Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Metal Ion Binding
	Biological Process	TRNA Threonylcarbamoyladenosine Modification	Regulation Of Transcription By RNA Polymerase II Viral Process
Pathways		tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Food addiction ( 27106561)	B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025) Chronic lymphocytic leukemia ( 18758461 28165464 24292274) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Subcutaneous adipose tissue ( 26480920)
Interacting Genes		25 interacting genes: CIAPIN1 CRIP2 EMCN GP1BA HPS6 LAGE3 LENG1 MUC1 NR3C1 NVL OPTC PDE4DIP PKP4 RBM48 REX1BD SF3B3 SHC1 SP110 SPRED1 TNS1 TP53RK WDR82 WIZ ZNF579 ZNF775	11 interacting genes: ANXA7 CDKN1A NAP1L2 NDUFV2 OSGEP RUNX3 SMN1 TK1 TSC22D1 TTR ZSCAN9
Entrez ID		55644	3431
HPRD ID		10133	06832
Ensembl ID		ENSG00000092094	ENSG00000135899
Uniprot IDs		Q9NPF4	Q9HB58
PDB IDs		6GWJ
Enriched GO Terms of Interacting Partners?
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