OSGEP and PKP4

Data Source:
BioGRID (two hybrid)

		OSGEP	PKP4
Description		O-sialoglycoprotein endopeptidase	plakophilin 4
Image			No pdb structure
GO Annotations	Cellular Component	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Plasma Membrane Nuclear Speck	Spindle Pole Cornified Envelope Nucleus Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Adherens Junction Cytoplasmic Side Of Plasma Membrane Cell Junction Desmosome Midbody Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Spindle Midzone Mitotic Spindle
	Molecular Function	Protein Binding Metal Ion Binding N(6)-L-threonylcarbamoyladenine Synthase Activity	Protein Binding Cadherin Binding
	Biological Process	TRNA Threonylcarbamoyladenosine Modification	Cell-cell Junction Assembly Cell-cell Signaling Regulation Of Cell Adhesion Keratinization Positive Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Cornification Cell-cell Adhesion
Pathways		tRNA modification in the nucleus and cytosol	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Food addiction ( 27106561)	Borderline personality disorder ( 28632202) Obesity-related traits ( 23251661) Restless legs syndrome ( 29029846)
Interacting Genes		25 interacting genes: CIAPIN1 CRIP2 EMCN GP1BA HPS6 LAGE3 LENG1 MUC1 NR3C1 NVL OPTC PDE4DIP PKP4 RBM48 REX1BD SF3B3 SHC1 SP110 SPRED1 TNS1 TP53RK WDR82 WIZ ZNF579 ZNF775	19 interacting genes: ATPAF2 CDH1 CDH2 CDH5 DSC3 DSP ERBIN GABARAP GOLGA2 LNX1 LZTS2 MINK1 OSGEP PAXIP1 PDZD2 PGAM1 PSEN1 TRIM23 UBASH3B
Entrez ID		55644	8502
HPRD ID		10133	05043
Ensembl ID		ENSG00000092094	ENSG00000144283
Uniprot IDs		Q9NPF4	Q99569
PDB IDs		6GWJ
Enriched GO Terms of Interacting Partners?
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