PKP4 and PGAM1

Data Source:
HPRD (two hybrid)

		PKP4	PGAM1
Description		plakophilin 4	phosphoglycerate mutase 1
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cornified Envelope Nucleus Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Adherens Junction Cytoplasmic Side Of Plasma Membrane Cell Junction Desmosome Midbody Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Spindle Midzone Mitotic Spindle	Extracellular Region Cytoplasm Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Cadherin Binding	Bisphosphoglycerate Mutase Activity Phosphoglycerate Mutase Activity Protein Binding Hydrolase Activity Protein Kinase Binding
	Biological Process	Cell-cell Junction Assembly Cell-cell Signaling Regulation Of Cell Adhesion Keratinization Positive Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Cornification Cell-cell Adhesion	Gluconeogenesis Glycolytic Process Regulation Of Glycolytic Process Neutrophil Degranulation Regulation Of Pentose-phosphate Shunt Respiratory Burst Canonical Glycolysis
Pathways		Keratinization Formation of the cornified envelope	Neutrophil degranulation Glycolysis Gluconeogenesis
Drugs			Copper Artenimol
Diseases
GWAS		Borderline personality disorder ( 28632202) Obesity-related traits ( 23251661) Restless legs syndrome ( 29029846)
Interacting Genes		19 interacting genes: ATPAF2 CDH1 CDH2 CDH5 DSC3 DSP ERBIN GABARAP GOLGA2 LNX1 LZTS2 MINK1 OSGEP PAXIP1 PDZD2 PGAM1 PSEN1 TRIM23 UBASH3B	7 interacting genes: ARL4D DCTN1 ERBB2 PCNA PKP4 UNC5CL XRCC6
Entrez ID		8502	5223
HPRD ID		05043	01392
Ensembl ID		ENSG00000144283	ENSG00000171314
Uniprot IDs		Q99569	B7Z9E5 P18669 Q6FHU2
PDB IDs			1LJD 1YFK 1YJX 4GPI 4GPZ 5Y2I 5Y2U 5Y35 5Y64 5Y65 5ZRM 5ZS8 6ISN
Enriched GO Terms of Interacting Partners?
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