OSGEP and TP53RK

Data Source:
BioGRID (two hybrid)

		OSGEP	TP53RK
Description		O-sialoglycoprotein endopeptidase	TP53 regulating kinase
Image			No pdb structure
GO Annotations	Cellular Component	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Plasma Membrane Nuclear Speck	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Metal Ion Binding N(6)-L-threonylcarbamoyladenine Synthase Activity	P53 Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Hydrolase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	TRNA Threonylcarbamoyladenosine Modification	Protein Phosphorylation TRNA Processing TRNA Threonylcarbamoyladenosine Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator
Pathways		tRNA modification in the nucleus and cytosol	tRNA modification in the nucleus and cytosol Regulation of TP53 Activity through Phosphorylation
Drugs
Diseases
GWAS		Food addiction ( 27106561)	Dimensional psychopathology (Arousal) ( 29496196) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		25 interacting genes: CIAPIN1 CRIP2 EMCN GP1BA HPS6 LAGE3 LENG1 MUC1 NR3C1 NVL OPTC PDE4DIP PKP4 RBM48 REX1BD SF3B3 SHC1 SP110 SPRED1 TNS1 TP53RK WDR82 WIZ ZNF579 ZNF775	12 interacting genes: CALCOCO2 CHN2 CLK1 DCTN1 GORASP2 LRRC2 MDM2 MTUS2 OSGEP SYNE1 TP53 TPRKB
Entrez ID		55644	112858
HPRD ID		10133	12276
Ensembl ID		ENSG00000092094	ENSG00000172315
Uniprot IDs		Q9NPF4	Q96S44
PDB IDs		6GWJ
Enriched GO Terms of Interacting Partners?
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