DNAJC30 and PEX12

Data Source:
BioGRID (two hybrid)

		DNAJC30	PEX12
Description		DnaJ heat shock protein family (Hsp40) member C30	peroxisomal biogenesis factor 12
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Integral Component Of Membrane	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Peroxisomal Importomer Complex
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding
	Biological Process	ATP Biosynthetic Process Brain Development Regulation Of Mitochondrial ATP Synthesis Coupled Proton Transport	Protein Monoubiquitination Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination
Pathways			E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import
Drugs
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Blood protein levels ( 29875488) Malaria ( 31844061)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		31 interacting genes: APP AQP6 BEST2 CALN1 CREB3 EBP EXOSC6 FAM209A FATE1 FBXO7 GPX8 JAGN1 KASH5 LMNA LRRC25 MFSD14B MGST2 MRM1 MSMO1 OPRL1 PEX12 REEP4 RNF170 S100B SIGLEC12 SLC10A4 SLC35C2 SLC51A TMEM31 TMEM52B TMEM86B	36 interacting genes: ACSL5 ADIPOQ BNIP2 BTN2A2 C5orf46 CLDN10 COL8A2 CXCL16 CYBC1 DNAJC30 ERMP1 FA2H FKBP8 FXYD6 GJB2 IER3IP1 MARCHF2 MGLL NKG7 NRM PEX10 PEX19 PEX5 PNLIPRP1 PTPN9 RBFA SEC22A SEC61G SMCO4 SRGN STX8 THSD7B TMEM11 TMEM222 TREX1 TTPA
Entrez ID		84277	5193
HPRD ID		10303	03455
Ensembl ID		ENSG00000176410	ENSG00000108733
Uniprot IDs		B3KSU4 Q96LL9	O00623
PDB IDs		2YUA
Enriched GO Terms of Interacting Partners?
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