RANBP9 and ADAP2

Data Source:
BioGRID (pull down)

		RANBP9	ADAP2
Description		RAN binding protein 9	ArfGAP with dual PH domains 2
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Nuclear Body	Cytoplasm Mitochondrial Envelope Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Enzyme Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Protein-macromolecule Adaptor Activity Phosphatidylinositol-3,4-bisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding Metal Ion Binding
	Biological Process	MAPK Cascade Cytoskeleton Organization Microtubule Nucleation Cell Surface Receptor Signaling Pathway Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process	Heart Development Positive Regulation Of GTPase Activity Inositol Lipid-mediated Signaling
Pathways		L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling
Drugs
Diseases
GWAS		Breast cancer ( 29059683 23535729)	Height ( 28552196) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5	9 interacting genes: APP EEF1G IKBKG NCL NEDD4L PRNP RANBP9 SNCA TUBB
Entrez ID		10048	55803
HPRD ID		04835	16357
Ensembl ID		ENSG00000010017	ENSG00000184060
Uniprot IDs		A0A024QZW3 Q96S59	Q2V6Q1 Q9NPF8
PDB IDs		5JI7 5JI9 5JIU
Enriched GO Terms of Interacting Partners?
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