RANBP9 and MPHOSPH8

Data Source:
HPRD (two hybrid)

		RANBP9	MPHOSPH8
Description		RAN binding protein 9	M-phase phosphoprotein 8
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Nuclear Body	Nucleosome Heterochromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Binding Enzyme Binding	Chromatin Binding Protein Binding Methylated Histone Binding
	Biological Process	MAPK Cascade Cytoskeleton Organization Microtubule Nucleation Cell Surface Receptor Signaling Pathway Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process	Regulation Of DNA Methylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Transcription, DNA-templated Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly
Pathways		L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling
Drugs
Diseases
GWAS		Breast cancer ( 29059683 23535729)
Interacting Genes		56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5	5 interacting genes: H3C1 MTRNR2L1 RANBP9 SH3BP4 SIRT1
Entrez ID		10048	54737
HPRD ID		04835	13682
Ensembl ID		ENSG00000010017	ENSG00000196199
Uniprot IDs		A0A024QZW3 Q96S59	Q99549
PDB IDs		5JI7 5JI9 5JIU	3LWE 3QO2 3R93 3SVM 6V2S
Enriched GO Terms of Interacting Partners?
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