Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
RANBP9 and ITGB2
Data Source:
HPRD
(in vitro, in vivo)
RANBP9
ITGB2
Description
RAN binding protein 9
integrin subunit beta 2
Image
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Microtubule Associated Complex
Plasma Membrane
Nuclear Body
Plasma Membrane
Focal Adhesion
Integrin Complex
External Side Of Plasma Membrane
Cell Surface
Membrane
Integrin AlphaL-beta2 Complex
Integrin AlphaM-beta2 Complex
Integrin AlphaX-beta2 Complex
Specific Granule Membrane
Receptor Complex
Plasma Membrane Raft
Extracellular Exosome
Tertiary Granule Membrane
Cytoplasmic Region
Ficolin-1-rich Granule Membrane
Extracellular Vesicle
Molecular Function
Protein Binding
Enzyme Binding
Amyloid-beta Binding
Complement Component C3b Binding
Integrin Binding
Protein Binding
Protein Kinase Binding
ICAM-3 Receptor Activity
Heat Shock Protein Binding
Cargo Receptor Activity
Metal Ion Binding
Cell Adhesion Molecule Binding
Biological Process
MAPK Cascade
Cytoskeleton Organization
Microtubule Nucleation
Cell Surface Receptor Signaling Pathway
Axon Guidance
Protein-containing Complex Assembly
Negative Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Amyloid Precursor Protein Catabolic Process
Microglial Cell Activation
Leukocyte Migration Involved In Inflammatory Response
Receptor-mediated Endocytosis
Phagocytosis, Engulfment
Apoptotic Process
Inflammatory Response
Cell Adhesion
Leukocyte Cell-cell Adhesion
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Cell-cell Signaling
Aging
Regulation Of Cell Shape
Cell Migration
Cytokine-mediated Signaling Pathway
Natural Killer Cell Activation
Extracellular Matrix Organization
Neutrophil Chemotaxis
Receptor Internalization
Positive Regulation Of Superoxide Anion Generation
Cell Adhesion Mediated By Integrin
Heterotypic Cell-cell Adhesion
Toll-like Receptor 4 Signaling Pathway
Endodermal Cell Differentiation
Receptor Clustering
Neutrophil Degranulation
Positive Regulation Of Neutrophil Degranulation
Endothelial Cell Migration
Cellular Extravasation
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Angiogenesis
Negative Regulation Of Dopamine Metabolic Process
Regulation Of Peptidyl-tyrosine Phosphorylation
Regulation Of Immune Response
Leukocyte Migration
Positive Regulation Of NF-kappaB Transcription Factor Activity
Cellular Response To Low-density Lipoprotein Particle Stimulus
Positive Regulation Of Protein Targeting To Membrane
Amyloid-beta Clearance
Cell-cell Adhesion
Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Positive Regulation Of Neuron Death
Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Neutrophil Migration
Positive Regulation Of Prostaglandin-E Synthase Activity
Pathways
L1CAM interactions
RAF/MAP kinase cascade
MET activates RAS signaling
Toll Like Receptor 4 (TLR4) Cascade
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Cell surface interactions at the vascular wall
Integrin cell surface interactions
Interleukin-4 and Interleukin-13 signaling
Neutrophil degranulation
Drugs
Diseases
Leukocyte adhesion deficiency (LAD), including the following four diseases: Leukocyte adhesion deficiency (I); Leukocyte adhesion deficiency (II); Leukocyte adhesion deficiency (III); LAD with Rac2 deficiency
GWAS
Breast cancer (
29059683
23535729
)
Heel bone mineral density (
28869591
)
Lymphocyte counts (
32888494
)
Monocyte count (
32888494
)
Interacting Genes
56 interacting genes:
ADAP1
ADAP2
APC
AR
ATM
AXL
BACE1
BRCA1
CACNA1G
CALB1
CBS
CCND1
CDK11B
CLEC7A
DDX4
DISC1
DYRK1B
ENTPD1
ESR1
EXOC2
FMR1
HIPK2
HMBS
HNF4G
ITGAL
ITGB2
L1CAM
LMNA
MAPK6
MET
MPHOSPH8
NCOA6
NCOR2
NSRP1
PPARD
PPARG
PPP1CA
PRKACA
RAF1
RAN
S100A7
SMAD2
SMAD3
SMAD9
SOS1
SPOP
SPP1
TFRC
THRA
THRB
TP53
TP73
UCHL1
USP11
WNK1
YPEL5
56 interacting genes:
ADAMTSL4
APOL2
C3
CD14
CD226
CD82
COPS3
COPS5
CYSRT1
CYTH1
CYTH2
DAB1
DOK1
EGFR
ESM1
FCER2
FHL2
FUT4
HP
ICAM1
ICAM2
ICAM3
ICAM4
ICAM5
ILK
ITGAD
ITGAM
ITGAX
KNG1
KRT31
KRTAP10-8
LHFPL5
MS4A7
MTIF3
NBPF19
NOTCH2NLA
NUMB
PRKCA
PRKCB
PRKCD
PRKCE
PRKCG
PRKCH
PRTN3
PTK2
PTK2B
RACK1
RANBP9
RDX
SCML1
SHARPIN
SYK
TLN1
TM4SF18
UPK1B
VNN2
Entrez ID
10048
3689
HPRD ID
04835
02506
Ensembl ID
ENSG00000010017
ENSG00000160255
Uniprot IDs
A0A024QZW3
Q96S59
A0A494C0X7
B4E0R1
P05107
PDB IDs
5JI7
5JI9
5JIU
1JX3
1L3Y
1YUK
2JF1
2P26
2P28
2V7D
3K6S
3K71
3K72
4NEH
4NEN
5E6R
5E6S
5E6U
5E6V
5E6W
5E6X
5ES4
5XR1
5ZAZ
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?