SGCB and SGCA

Data Source:
HPRD (in vivo)

		SGCB	SGCA
Description		sarcoglycan beta	sarcoglycan alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Integral Component Of Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Sarcolemma	Cytoplasm Cytoskeleton Cell-cell Junction Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Integral Component Of Membrane Sarcolemma Membrane Raft
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Muscle Organ Development Muscle Fiber Development Cardiac Muscle Cell Development Vascular Associated Smooth Muscle Cell Development	Muscle Contraction Muscle Organ Development Response To Denervation Involved In Regulation Of Muscle Adaptation Skeletal Muscle Tissue Regeneration
Pathways
Drugs
Diseases		Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD)	Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD)
GWAS			Heel bone mineral density ( 30598549) Temporomandibular joint disorder ( 28081371) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		22 interacting genes: ADAM33 ADRA1A APOL3 BRICD5 CLEC7A CMTM5 EHHADH HTR2C LTB4R2 MAL MGST2 NINJ1 PTTG1IP SGCA SGCD SGCG SGCZ SLC52A1 SMIM3 TMEM11 TNF TRIM63	8 interacting genes: FN1 FSTL1 ITGB1BP2 SGCB SGCD SGTA SGTB TAF1
Entrez ID		6443	6442
HPRD ID		02942	02525
Ensembl ID		ENSG00000163069	ENSG00000108823
Uniprot IDs		Q16585 Q5U0N0	A0A0S2Z4P8 A0A0S2Z4Q1 Q16586
PDB IDs
Enriched GO Terms of Interacting Partners?
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