DYNLT1 and UXT

Data Source:
BioGRID (two hybrid)

		DYNLT1	UXT
Description		dynein light chain Tctex-type 1	ubiquitously expressed prefoldin like chaperone
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen	Chromatin Spindle Pole Gamma-tubulin Complex Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton
	Molecular Function	Motor Activity Protein Binding Protein C-terminus Binding Identical Protein Binding	Chromatin Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Neutrophil Degranulation Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus	Negative Regulation Of Transcription By RNA Polymerase II Microtubule Cytoskeleton Organization Regulation Of Transcription By RNA Polymerase II Apoptotic Process Centrosome Cycle Mitochondrion Transport Along Microtubule Negative Regulation Of G0 To G1 Transition
Pathways		Neutrophil degranulation	Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS
Interacting Genes		50 interacting genes: ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RRAGA SDCBP SIRPA SVIL TCEANC TROAP TUBA3C TXN UXT VDAC1 XRN2	29 interacting genes: APP AR CECR2 DYNLT1 FBXO7 GLE1 KRT31 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP5-7 KRTAP5-9 LRPPRC LSM1 MACROD1 MCPH1 MPP1 NBPF19 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 VHL
Entrez ID		6993	8409
HPRD ID		15987	02209
Ensembl ID		ENSG00000146425	ENSG00000126756
Uniprot IDs		P63172	Q9UBK9
PDB IDs		5JPW
Enriched GO Terms of Interacting Partners?
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