DYNLT1 and DDX54

Data Source:
BioGRID (two hybrid)

		DYNLT1	DDX54
Description		dynein light chain Tctex-type 1	DEAD-box helicase 54
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen	Nucleus Nucleoplasm Nucleolus Golgi Apparatus Membrane
	Molecular Function	Motor Activity Protein Binding Protein C-terminus Binding Identical Protein Binding	Transcription Corepressor Activity RNA Binding RNA Helicase Activity Signaling Receptor Binding ATP Binding Estrogen Receptor Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Neutrophil Degranulation Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus	RRNA Processing RNA Processing RNA Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS			Body mass index ( 26426971) Response to fenofibrate (adiponectin levels) ( 23149075)
Interacting Genes		50 interacting genes: ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RRAGA SDCBP SIRPA SVIL TCEANC TROAP TUBA3C TXN UXT VDAC1 XRN2	19 interacting genes: APP CASK CSNK2A1 DVL3 DYNLT1 ESR1 ESR2 NEDD4 NEDD4L NR3C1 PGR PJA1 POLR2G PTPRD SEMA4A SMURF1 TMED9 YWHAE ZNF394
Entrez ID		6993	79039
HPRD ID		15987	13129
Ensembl ID		ENSG00000146425	ENSG00000123064
Uniprot IDs		P63172	Q8TDD1
PDB IDs		5JPW
Enriched GO Terms of Interacting Partners?
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