UXT and GLE1

Data Source:
BioGRID (two hybrid)

		UXT	GLE1
Description		ubiquitously expressed prefoldin like chaperone	GLE1 RNA export mediator
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Spindle Pole Gamma-tubulin Complex Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton	Extracellular Space Nuclear Envelope Nuclear Pore Nucleolus Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Ciliary Basal Body Nuclear Pore Cytoplasmic Filaments
	Molecular Function	Chromatin Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding	Inositol Hexakisphosphate Binding Protein Binding Phospholipid Binding Translation Initiation Factor Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Microtubule Cytoskeleton Organization Regulation Of Transcription By RNA Polymerase II Apoptotic Process Centrosome Cycle Mitochondrion Transport Along Microtubule Negative Regulation Of G0 To G1 Transition	MRNA Export From Nucleus Regulation Of Translational Initiation Regulation Of Translational Termination Poly(A)+ MRNA Export From Nucleus
Pathways		Transcriptional Regulation by E2F6	Transport of Mature mRNA derived from an Intron-Containing Transcript
Drugs
Diseases			Lethal arthrogryposis with anterior horn cell disease Lethal congenital contractural syndrome (LCCS)
GWAS			Axial length ( 24144296) Body mass index ( 26426971)
Interacting Genes		29 interacting genes: APP AR CECR2 DYNLT1 FBXO7 GLE1 KRT31 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP5-7 KRTAP5-9 LRPPRC LSM1 MACROD1 MCPH1 MPP1 NBPF19 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 VHL	4 interacting genes: KRT10 NUP155 NUP42 UXT
Entrez ID		8409	2733
HPRD ID		02209	04536
Ensembl ID		ENSG00000126756	ENSG00000119392
Uniprot IDs		Q9UBK9	B3KMG0 Q53GS7
PDB IDs			6B4F 6B4I 6B4J
Enriched GO Terms of Interacting Partners?
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